J
Jimena Cuenca
Researcher at University of Los Andes
Publications - 28
Citations - 2337
Jimena Cuenca is an academic researcher from University of Los Andes. The author has contributed to research in topics: Mesenchymal stem cell & Stem cell. The author has an hindex of 16, co-authored 23 publications receiving 1818 citations. Previous affiliations of Jimena Cuenca include University of Chile & University of the Andes, Chile.
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Journal ArticleDOI
Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation
Juan-Carlos Rodríguez-Prados,Paqui G. Través,Jimena Cuenca,Daniel Rico,Julián Aragonés,Paloma Martín-Sanz,Marta Cascante,Lisardo Boscá +7 more
TL;DR: Whether specific metabolic patterns depend on the signaling pathway activated is analyzed, and it is shown that activated macrophages are essentially glycolytic cells, and a clear cutoff between the classic/innate activation and the alternative pathway exists.
Journal ArticleDOI
Safety and Efficacy of the Intravenous Infusion of Umbilical Cord Mesenchymal Stem Cells in Patients With Heart Failure: A Phase 1/2 Randomized Controlled Trial (RIMECARD Trial [Randomized Clinical Trial of Intravenous Infusion Umbilical Cord Mesenchymal Stem Cells on Cardiopathy]).
Jorge Bartolucci,Fernando J. Verdugo,Paz Gonzalez,Ricardo Larrea,Ema Abarzua,Carlos Goset,Pamela Rojo,Iván Palma,Rubén Lamich,Pablo Pedreros,Gloria Valdivia,Valentina M. Lopez,Carolina Nazzal,Francisca Alcayaga-Miranda,Jimena Cuenca,Matthew Brobeck,Amit N. Patel,Fernando E Figueroa,Maroun Khoury +18 more
TL;DR: In this article, the authors evaluated the safety and efficacy of the infusion of UC-MSC in patients with chronic stable HFrEF under optimal medical treatment and found that the infusion resulted in a 55-fold increase in the expression of Hepatocyte Growth Factor (HGF), known to be involved in cell migration and immunoregulation.
Journal ArticleDOI
Current status of cell-based therapies for respiratory virus infections: applicability to COVID-19.
Maroun Khoury,Jimena Cuenca,Fernanda F. Cruz,Fernanda F. Cruz,Fernando E Figueroa,Patricia R. M. Rocco,Patricia R. M. Rocco,Daniel J. Weiss +7 more
TL;DR: It is imperative to better comprehend the rationale and underlying data that both support and refute effectiveness of MSCs in respiratory virus infections, and to define the targeted patient population and potential cell therapy approaches for COVID-19.
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Antimicrobial Activity of Mesenchymal Stem Cells: Current Status and New Perspectives of Antimicrobial Peptide-Based Therapies.
TL;DR: In this paper, the role of mesenchymal stem cells (MSCs) in the secretion of antimicrobial peptides and proteins (AMPs) has been investigated in pre-clinical models of sepsis, acute respiratory distress syndrome and cystic fibrosis related infections.
Journal ArticleDOI
Characterization of menstrual stem cells: angiogenic effect, migration and hematopoietic stem cell support in comparison with bone marrow mesenchymal stem cells
Francisca Alcayaga-Miranda,Jimena Cuenca,Patricia Luz-Crawford,Carolina Aguila-Díaz,Ainoa Fernandez,Fernando E Figueroa,Maroun Khoury +6 more
TL;DR: Evidence is presented showing superiority of MenSCs with respect to several functional aspects, in comparison with BM-MSCs, with regards to proliferation, lineage differentiation, migration potential, secretion profile and angiogenic properties in vitro and in a matrigel plug assay in mice.