Jing Zhou

TL;DR: The properties suggest that HSP27, HSP70 and HSP90 are appropriate targets for modulating cell death pathways, and the emerging strategies that have been developed for cancer therapy based on the inhibition of the three HSPs are summarized.

TL;DR: It is shown that the non-small cell lung cancer (NSCLC) cell lines treated with OP-B grow more slowly and accumulate vacuoles in their cytoplasm compared to untreated control cells and activation of the PI3K/Akt/mTOR signaling pathway provides evidence that activation of this pathway may correlate with induction of autophagy in H460 cells.

TL;DR: The pharmacokinetics of four classical Chinese medicines for therapy of cerebrovascular disease containing Panax notoginseng, Salvia miltiorrhiza, Ligusticum Chuanxiong and Gardenia are compiled and discussed, providing a convenient reference for researchers to increase efficiency of drug discovery.

TL;DR: Experimental evidence is provided to support the development of GA as a chemotherapeutic agent for NSCLC and it is shown that GA suppressed the proliferation of A549 and NCI-H460 cells.

TL;DR: It is demonstrated that Lf-NPs of α-asarone have potential as a carrier for nose-to-brain delivery of α -asarone for brain diseases and could enhance the efficacy of brain targeting with NPs and reduce its liver accumulation.