J
Jinhua Wu
Researcher at Chinese Academy of Sciences
Publications - 63
Citations - 2208
Jinhua Wu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Lysophosphatidic acid & Receptor. The author has an hindex of 24, co-authored 63 publications receiving 1898 citations. Previous affiliations of Jinhua Wu include Florida Atlantic University & Sichuan University.
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Journal ArticleDOI
Quercetin induces protective autophagy in gastric cancer cells: involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling.
Kui Wang,Rui Liu,Jingyi Li,Jiali Mao,Yunlong Lei,Jinhua Wu,Jun Zeng,Tao Zhang,Hong Wu,Lijuan Chen,Canhua Huang,Yuquan Wei +11 more
TL;DR: Functional studies revealed that quercetin activated autophagy by modulation of Akt-mTOR signaling and hypoxia-induced factor 1α (HIF-1α) signaling, and a xenograft model provided additional evidence for occurrence of quercETin-induced apoptosis and Autophagy in vivo.
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Role of LPA4/p2y9/GPR23 in negative regulation of cell motility.
Zendra Lee,Ching-Ting Cheng,Helen Zhang,Mark A. Subler,Jinhua Wu,Abir Mukherjee,Jolene J. Windle,Ching-Kang Chen,Xianjun Fang +8 more
TL;DR: Targeted disruption of lpa(4) in mice provides genetic and biochemical evidence that LPA( 4) is a suppressor of LPA-dependent cell migration and invasion in contrast to the motility-stimulating Edg LPA receptors.
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RNA Damage and Surveillance under Oxidative Stress
TL;DR: Collective evidence suggests that RNA oxidative damage is a challenging and persistent problem normally controlled through RNA surveillance mechanisms, making them critical to maintaining cellular health and preventing disease.
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Inhibition of calcium-independent phospholipase A2 suppresses proliferation and tumorigenicity of ovarian carcinoma cells.
Yuanda Song,Palmer Wilkins,Wenhui Hu,Karnam S. Murthy,Jing Chen,Zendra Lee,Regina A. Oyesanya,Jinhua Wu,Suzanne E. Barbour,Xianjun Fang +9 more
TL;DR: An essential role is shown for iPLA2 in cell cycle progression and tumorigenesis of ovarian carcinoma cells through G2/M-phase arrest.
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Characterization of RNA damage under oxidative stress in Escherichia coli.
TL;DR: The data suggests that RNA is a primary target for reactive oxygen species and RNA oxidation is part of the paradox that cells have to deal with under oxidative stress, and highly folded RNA is not protected from oxidation.