Kui Wang

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: This work presents a direct multivariate finite mixture modeling approach, using skew and heavy-tailed distributions, to address the complexities of flow cytometric analysis and to deal with high-dimensional cytometric data without the need for projection or transformation.

TL;DR: A voltage-fluctuation-suppression method which can reduce the amplitude of the voltage fluctuation in low-frequency region and improve the start-up performance significantly is proposed.

TL;DR: Functional studies revealed that quercetin activated autophagy by modulation of Akt-mTOR signaling and hypoxia-induced factor 1α (HIF-1α) signaling, and a xenograft model provided additional evidence for occurrence of quercETin-induced apoptosis and Autophagy in vivo.

TL;DR: This work comprehensively characterized intrinsic disorder at proteomic and protein levels from all significant perspectives, including abundance, cellular localization, functional roles, evolution, and impact on structural coverage, and shows that intrinsic disorder is more abundant and has a unique profile in eukaryotes.