J
Jiri J. Frohlich
Researcher at University of British Columbia
Publications - 24
Citations - 3164
Jiri J. Frohlich is an academic researcher from University of British Columbia. The author has contributed to research in topics: Cholesterol & Lipoprotein. The author has an hindex of 18, co-authored 24 publications receiving 3110 citations. Previous affiliations of Jiri J. Frohlich include St. Paul's Hospital.
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Journal ArticleDOI
Simvastatin and Niacin, Antioxidant Vitamins, or the Combination for the Prevention of Coronary Disease
B.G. Brown,Xue-Qiao Zhao,Alan Chait,L D Fisher,M.C. Cheung,Josh S. Morse,Alice Dowdy,Emily K Marino,Bolson El,Petar Alaupovic,Jiri J. Frohlich,John J. Albers +11 more
TL;DR: Simvastatin plus niacin provides marked clinical and angiographically measurable benefits in patients with coronary disease and low HDL levels, and the use of antioxidant vitamins in this setting must be questioned.
Journal ArticleDOI
Age and residual cholesterol efflux affect HDL cholesterol levels and coronary artery disease in ABCA1 heterozygotes
Susanne M. Clee,J.J.P. Kastelein,M. Van Dam,Michel Marcil,Kirsten Roomp,K.Y. Zwarts,Jennifer A. Collins,R. Roelants,Naoki Tamasawa,Tomáš Štulc,Toshihiro Suda,Richard Ceska,Betsie Boucher,C. Rondeau,C. DeSouich,Angela Brooks-Wilson,H.O. Molhuizen,Jiri J. Frohlich,Jacques Genest,Michael R. Hayden +19 more
TL;DR: Data provide direct evidence that impairment of cholesterol efflux and consequently reverse cholesterol transport is associated with reduced plasma HDL-C levels and increased risk of CAD.
Report of the Working Group on Hypercholesterolemia and Other Dyslipidemias
TL;DR: The causal relation between hypercholesterolemia and atherosclerosis was established more than 80 years ago by Anitschkow as mentioned in this paper, and the results of these early clinical studies and the extensive epidemiological data on the relation between plasma lipoprotein levels and CAD, as well as experimental information from animal models of coronary diseases, led to the development of policies to manage and treat lipid disorders.
Journal ArticleDOI
Advances in experimental dyslipidemia and atherosclerosis.
TL;DR: Evidence suggests that among wild-type species, strains of White Carneau pigeons and Watanabe Heritable Hyperlipidemic and St. Thomas’s Hospital rabbits are preferable to the cholesterol-fed wild- type animal species in dyslipidemia and atherosclerosis research.