J
Jiří Widimský
Researcher at First Faculty of Medicine, Charles University in Prague
Publications - 135
Citations - 2539
Jiří Widimský is an academic researcher from First Faculty of Medicine, Charles University in Prague. The author has contributed to research in topics: Blood pressure & Essential hypertension. The author has an hindex of 27, co-authored 135 publications receiving 2113 citations. Previous affiliations of Jiří Widimský include Hotel Dieu Hospital & Charles University in Prague.
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Journal ArticleDOI
Randomized Comparison of Renal Denervation Versus Intensified Pharmacotherapy Including Spironolactone in True-Resistant Hypertension : Six-Month Results From the Prague-15 Study
Ján Rosa,Petr Widimský,Petr Tousek,Ondřej Petrák,Karol Curila,Petr Waldauf,František Bednář,Tomáš Zelinka,Robert Holaj,Branislav Štrauch,Z. Somloova,Miloš Táborský,Jan Václavík,Eva Kociánová,Marian Branny,Igor Nykl,Otakar Jiravský,Jiří Widimský +17 more
TL;DR: In this article, a prospective, randomized, open-label multicenter trial evaluated the efficacy of catheter-based renal denervation (Symplicity, Medtronic) versus intensified pharmacological treatment including spironolactone (if tolerated) in patients with true-resistant hypertension.
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Precise assessment of noncompliance with the antihypertensive therapy in patients with resistant hypertension using toxicological serum analysis.
Branislav Štrauch,Ondřej Petrák,Tomáš Zelinka,Ján Rosa,Z. Somloova,T. Indra,Lukáš Chytil,Věra Marešová,Ivana Kurcová,Robert Holaj,Dan Wichterle,Jiří Widimský +11 more
TL;DR: Evaluation of antihypertensive drugs concentrations is a useful and precise method for assessment of noncompliance in patients with resistant hypertension and is useful before starting the diagnostic work-up of secondary forms of hypertension and before assignment patients into protocols with new therapy modalities such as renal denervation.
Journal ArticleDOI
Risk Factors for Nonadherence to Antihypertensive Treatment
Pankaj Gupta,Prashanth Patel,Branislav Štrauch,Florence Lai,Artur Akbarov,Věra Marešová,Christobelle White,Ondřej Petrák,Gaurav S Gulsin,Veena Patel,Ján Rosa,Richard Lee Cole,Tomáš Zelinka,Robert Holaj,Angela Kinnell,Paul R. Smith,John R. Thompson,Iain Squire,Iain Squire,Jiří Widimský,Nilesh J. Samani,Nilesh J. Samani,Bryan Williams,Maciej Tomaszewski +23 more
TL;DR: It is demonstrated that the number and class of prescribed antihypertensives are modifiable risk factors for biochemically confirmed nonadherence to blood pressure–lowering therapy and further development of discriminatory models incorporating these parameters might prove clinically useful in assessment ofnonadherence in countries where biochemical analysis is unavailable.
Journal ArticleDOI
High incidence of cardiovascular complications in pheochromocytoma.
Tomáš Zelinka,Ondřej Petrák,Hana Turkova,Robert Holaj,Branislav Štrauch,Michal Krsek,A Vránková,Zdeněk Musil,Jaroslava Dušková,J. Kubinyi,David Michalský,Květoslav Novák,Jiří Widimský +12 more
TL;DR: These data show relatively high incidence of cardiovascular complications in subjects with pheochromocytoma, but these subjects did not differ significantly from subjects without complications in age, gender, body mass index, paroxysmal symptoms, symptom duration, tumor dimension, catecholamine secretory phenotype, and incidence of hypertension or diabetes mellitus.
Journal ArticleDOI
Biochemical Screening for Nonadherence Is Associated With Blood Pressure Reduction and Improvement in Adherence.
Pankaj Gupta,Prashanth Patel,Prashanth Patel,Prashanth Patel,Branislav Štrauch,Florence Lai,Artur Akbarov,Gaurav S Gulsin,Alison Beech,Věra Marešová,Peter S. Topham,Adrian G. Stanley,Herbert Thurston,Paul R. Smith,Rob Horne,Jiří Widimský,Bernard Keavney,Anthony M. Heagerty,Nilesh J. Samani,Bryan Williams,Maciej Tomaszewski +20 more
TL;DR: Data show that nonadherent hypertensive patients respond to liquid chromatography–tandem mass spectrometry-based biochemical analysis with improved adherence and significant BP drop, and such repeated biochemical analyses should be considered as a therapeutic approach in nonadherence hypertensive Patients.