Joachim O. Rädler

TL;DR: The addition of either linear λ-phage or plasmid DNA to CLs resulted in an unexpected topological transition from liposomes to optically birefringent liquid-crystalline condensed globules, revealing a novel multilamellar structure with alternating lipid bilayer and DNA monolayers.

TL;DR: Optical microscopy revealed that the LalphaC complexes bind stably to anionic vesicles (models of cellular membranes), whereas the more transfectant HIIC complexes are unstable and rapidly fuse and release DNA upon adhering to anionics.

TL;DR: In this article, a general strategy is described which allows for transferring hydrophobically capped nanocrystals from organic to aqueous solution by wrapping an amphiphilic polymer around the particles.

TL;DR: The existence of two distinct time scales in the protein off-kinetics, for both NP types studied here, indicates the possibility of an exposure memory effect in the NP corona, as well as a single, universal adsorption curve.

TL;DR: In this article, the conformation of DNA molecules electrostatically bound to fluid cationic lipid bilayers was investigated by fluorescence microscopy, and the DNA diffuses freely in the plane and follows Rouse dynamics,D, 1yN, with an increasing number of base pairs N. The chain extension scales as kR2l, N2n, with n ­ 0.79 6 0.04 in good agreement with the exact exponent n ­ 3y4 for a selfavoiding random walk in two dimensions.