J
Joan Petro
Researcher at Repligen Corporation
Publications - 2
Citations - 769
Joan Petro is an academic researcher from Repligen Corporation. The author has contributed to research in topics: Endothelial stem cell & Platelet factor 4. The author has an hindex of 1, co-authored 2 publications receiving 759 citations.
Papers
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Journal ArticleDOI
Inhibition of angiogenesis by recombinant human platelet factor-4 and related peptides.
Theodore E. Maione,Gary S. Gray,Joan Petro,Anthony J. Hunt,Amy L. Donner,Susan I. Bauer,Helen F. Carson,Richard J. Sharpe,Richard J. Sharpe +8 more
TL;DR: Recombinant human platelet factor-4 (rhPF4), purified from Escherichia coli, inhibited blood vessel proliferation in the chicken chorioallantoic membrane in a dose-dependent manner and suggested that the angiostatic effect was due to specific inhibition of growth factor-stimulated endothelial cell proliferation.
Patent
Novel prokaryotic expression and secretion system
TL;DR: In this article, a recombinant DNA expression/secretion system for prokaryotic organisms to produce useful proteins was proposed. But the system can be used to have proteins secreted by an engineered host where normally the proteins are not secreted at all by the host.