Joanne F. Doleman

TL;DR: Microarrays were employed to analyze gene transcription in peripheral blood mononuclear cells prepared from serial blood samples that had been obtained, at weekly intervals, from apparently healthy human volunteers, to provide evidence that the gene transcription profiles of sampled tissues can be comparatively stable over time.

TL;DR: Evidence from two independent human studies indicates that consumption of high glucoraphanin broccoli significantly reduces plasma LDL-C.

TL;DR: It is concluded that OE33 is a useful model for the study of COX-2 expression and associated phenomena in human adenocarcinoma cells in vitro, and future studies should assess their effects in vivo.

TL;DR: It is shown that sulforaphane suppresses transcriptional changes induced by PTEN deletion and induces additional changes in gene expression associated with cell cycle arrest and apoptosis in PTEN null tissue, but has no effect on transcription in wild type tissue.

TL;DR: The increased consumption of Brassica vegetables was linked to a reduced relative abundance of SRB, and therefore may be potentially beneficial to gastrointestinal health.