Praise for the Third Edition: "This is one of the best books available. Its excellent organizational structure allows quick reference to specific models and its clear presentation . . . solidifies the understanding of the concepts being presented."IIE Transactions on Operations EngineeringThoroughly revised and expanded to reflect the latest developments in the field, Fundamentals of Queueing Theory, Fourth Edition continues to present the basic statistical principles that are necessary to analyze the probabilistic nature of queues. Rather than presenting a narrow focus on the subject, this update illustrates the wide-reaching, fundamental concepts in queueing theory and its applications to diverse areas such as computer science, engineering, business, and operations research.This update takes a numerical approach to understanding and making probable estimations relating to queues, with a comprehensive outline of simple and more advanced queueing models. Newly featured topics of the Fourth Edition include:Retrial queuesApproximations for queueing networksNumerical inversion of transformsDetermining the appropriate number of servers to balance quality and cost of serviceEach chapter provides a self-contained presentation of key concepts and formulae, allowing readers to work with each section independently, while a summary table at the end of the book outlines the types of queues that have been discussed and their results. In addition, two new appendices have been added, discussing transforms and generating functions as well as the fundamentals of differential and difference equations. New examples are now included along with problems that incorporate QtsPlus software, which is freely available via the book's related Web site.With its accessible style and wealth of real-world examples, Fundamentals of Queueing Theory, Fourth Edition is an ideal book for courses on queueing theory at the upper-undergraduate and graduate levels. It is also a valuable resource for researchers and practitioners who analyze congestion in the fields of telecommunications, transportation, aviation, and management science.

Fundamentals of Queueing Theory

(1963). Statistical Inference for Markov Processes. Technometrics: Vol. 5, No. 3, pp. 413-415.

Statistical Inference for Markov Processes

Kaempferol, a natural flavonoid present in several plants, possesses a wide range of therapeutic properties such as antioxidant, anticancer, and anti-inflammatory. It has a significant role in reducing cancer and can act as a therapeutic agent in the treatment of diseases and ailments such as diabetes, obesity, cardiovascular diseases, oxidative stress, asthma, and microbial contamination disorders. Kaempferol acts through different mechanisms: It induces apoptosis (HeLa cervical cancer cells), decreases cell viability (G2/M phase), downregulates phosphoinositide 3-kinase (PI3K)/AKT (protein kinase B) and human T-cell leukemia/lymphoma virus-I (HTLV-I) signaling pathways, suppresses protein expression of epithelial-mesenchymal transition (EMT)-related markers including N-cadherin, E-cadherin, Slug, and Snail, and metastasis-related markers such as matrix metallopeptidase 2 (MMP-2). Accordingly, the aim of the present review is to collect information pertaining to the effective role of kaempferol against various degenerative disorders, summarize the antioxidant, anti-inflammatory, anticancer, antidiabetic, and antiaging effects of kaempferol and to review the progress of recent research and available data on kaempferol as a protective and chemotherapeutic agent against several ailments.

Chemo-preventive and therapeutic effect of the dietary flavonoid kaempferol: A comprehensive review

Statistical Inference for Stochastic Processes.

An ethnopharmacological survey of medicinal plants traditionally used for cancer treatment in the Ashanti region, Ghana.

Structural characterization of a novel derivative of myricetin from Mimosa pudica as an anti-proliferative agent for the treatment of cancer.

Objective: The present study was designed to determine the comparative anticancer activities of flavonoids isolated from Aloe vera, Mimosa pudica and Phyllanthus niruri against human breast carcinoma cell line (MCF-7) using MTT assay. Methods: MTT-based cytotoxicity activity study against human breast carcinoma cell line (MCF-7) was conducted to evaluate the potent activity of flavonoids isolated from Aloe vera, Mimosa pudica and Phyllanthus niruri. Thin Layer Chromatography (TLC) and Fourier Transform Infra-Red (FTIR) spectra were recorded which confirmed the presence of flavonoids in the methanolic extracts. Results: Flavonoids isolated from Aloe vera, Mimosa pudica and Phyllanthus niruri showed cytotoxicity activity against human breast carcinoma cell line (MCF-7) and the inhibitory concentration at 50% growth (IC50) was found to be, Mimosa pudica (IC50= 35.52±0.50µg/ml), Aloe vera (IC50= 54.97±0.36µg/ml) and Phyllanthus niruri (IC50= 84.88±0.87µg/ml). Conclusion: The results indicated the cytotoxicity activity of all the three flavonoids isolated. Therefore, they can be effectively employed in anticancer treatment. Cytotoxic study suggested that flavonoid from Mimosa pudica has the maximum cytotoxic effect than flavonoid from Aloe vera and Phyllanthus niruri against MCF-7, Human breast cancer cell line (Mimosa pudica >Aloe vera >Phyllanthus niruri).

A comparative evaluation of anticancer activities of flavonoids isolated from mimosa pudica, aloe vera and phyllanthus niruri against human breast carcinoma cell line (mcf-7) using mtt assay

In this paper, the stress-strength reliability of single and multi-component systems are estimated assuming discrete phase type distribution for stress and strength components. The systems with str...

Estimation of stress-strength reliability using discrete phase type distribution

Introducing a new flexible model for lifetimes called Beta half Logistic distribution by compounding the Beta distribution and half logistic distributions, we explore its analytical characteristics and statistical properties. The maximum likelihood estimates of the model parameters are discussed and the usefulness of the new model is illustrated by means of data on remission times of bladder cancer patients.

Beta half logistic distribution – A new probability model for lifetime data

A new probability model obtained by generalizing the power transformed half logistic distribution is introduced by transforming the type II beta distribution. The basic properties of the distributi...

Joby K. Jose

Papers

Structural characterization of a novel derivative of myricetin from Mimosa pudica as an anti-proliferative agent for the treatment of cancer.

A comparative evaluation of anticancer activities of flavonoids isolated from mimosa pudica, aloe vera and phyllanthus niruri against human breast carcinoma cell line (mcf-7) using mtt assay

Estimation of stress-strength reliability using discrete phase type distribution

Beta half logistic distribution – A new probability model for lifetime data

A study of stress-strength reliability using a generalization of power transformed half-logistic distribution