Jocelyn M. Richard

TL;DR: This work assesses brain mechanisms known to generate "liking" and "wanting" for foods and evaluates their interaction with regulatory mechanisms of hunger and satiety, relevant to clinical issues.

TL;DR: By pairing cues with brief activation of dopamine neurons in absence of reward, the authors reveal elemental behaviors conditioned by dopamine, showing VTA underlies generation of incentive value and SNc supports conditioned movement invigoration.

TL;DR: It is concluded that local dopamine is needed to enable disruptions of corticolimbic glutamate signals in shell to generate either positive incentive salience or negative fearful salience (valence depending on site and other conditions).

TL;DR: Results from several lines of research are described that sprang in part from earlier findings by Ann Kelley, including hedonic hotspots for generating intense pleasure 'liking', separate identities of 'wanting' versus 'l liking' systems, a novel role for dorsal neostriatum in generating motivation to eat, and dynamic limbic transformations of learned memories into motivation.

TL;DR: A review of topics covered in a mini-symposium at the 2013 Society for Neuroscience annual meeting to determine how this system flexibly encodes and responds to positive and negative states and events, beyond simple associative learning.