J
Joe M. McCord
Researcher at Anschutz Medical Campus
Publications - 160
Citations - 40338
Joe M. McCord is an academic researcher from Anschutz Medical Campus. The author has contributed to research in topics: Superoxide dismutase & Superoxide. The author has an hindex of 65, co-authored 157 publications receiving 38979 citations. Previous affiliations of Joe M. McCord include Johns Hopkins University School of Medicine & University of South Alabama.
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Journal ArticleDOI
Superoxide Dismutase AN ENZYMIC FUNCTION FOR ERYTHROCUPREIN (HEMOCUPREIN)
Joe M. McCord,Irwin Fridovich +1 more
TL;DR: The demonstration that O2·- can reduce ferricytochrome c and tetranitromethane, and that superoxide dismutase, by competing for the superoxide radicals, can markedly inhibit these reactions, is demonstrated.
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Oxygen-derived free radicals in postischemic tissue injury.
TL;DR: It is now clear that oxygen-derived free radicals play an important part in several models of experimentally induced reperfusion injury, and Dysfunction induced by free radicals may be a major component of ischemic diseases of the heart, bowel, liver, kidney, and brain.
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The evolution of free radicals and oxidative stress
TL;DR: Redox regulation of gene expression by superoxide and other related oxidants and antioxidants is beginning to unfold as a vital mechanism in health and disease.
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Superoxide radicals in feline intestinal ischemia
TL;DR: The results of this study indicate that superoxide radicals are primarily responsible for the increased capillary permeability in the ischemic bowel.
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The Reduction of Cytochrome c by Milk Xanthine Oxidase
Joe M. McCord,Irwin Fridovich +1 more
TL;DR: The data are consistent with the conclusion that xanthine oxidase generates an unstable reduced form of oxygen, presumably the superoxide anion, and that this radical is the agent which directly reduces cytochrome c and initiates the sulfite-oxygen chain reaction.