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Joerg Hennenlotter

Researcher at University of Tübingen

Publications -  114
Citations -  2122

Joerg Hennenlotter is an academic researcher from University of Tübingen. The author has contributed to research in topics: Bladder cancer & Renal cell carcinoma. The author has an hindex of 21, co-authored 114 publications receiving 1916 citations.

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Economic aspects of bladder cancer: what are the benefits and costs?

TL;DR: New diagnostic tools such as urine markers may assist in more cost-effectively detecting BC at an earlier stage, however, these markers cannot replace the cystoscopy, which is the current standard of care.
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MRI-guided biopsy of the prostate increases diagnostic performance in men with elevated or increasing PSA levels after previous negative TRUS biopsies.

TL;DR: The method is safe, can be useful to select suspicious areas in the prostate, and has the potential to improve cancer detection rate in men with previous negative TRUS-biopsies.
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Expansion and differentiation of neural progenitors derived from the human adult enteric nervous system.

TL;DR: It is feasible to isolate and expand enteric progenitor cells from human adult tissue and these findings offer new strategies for enteric stem cell research and future cell-based therapies.
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DNA Methylation of the SLC16A3 Promoter Regulates Expression of the Human Lactate Transporter MCT4 in Renal Cancer with Consequences for Clinical Outcome

TL;DR: SLC16A3 promoter DNA methylation was identified as a novel epigenetic mechanism for MCT4 regulation in ccRCC with first evidence of a biological rationale for prognosis and clinical outcome.
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Hsa-mir-124-3 CpG island methylation is associated with advanced tumours and disease recurrence of patients with clear cell renal cell carcinoma.

TL;DR: Tumour-specific hypermethylation of mir-124-3 in samples of RCCs with clear cell histology (ccRCC) compared with paired normal appearing tissues was found and was identified as a relevant epigenetic mark for ccRCC thus underlining the need for functional studies of potentially affected signalling pathways in kidney tumour models.