Showing papers by "Johannes Beck published in 2012"
TL;DR: This study shows that a single treatment of the glabellar region with botulinum toxin may shortly accomplish a strong and sustained alleviation of depression in patients, who did not improve sufficiently on previous medication.
213 citations
TL;DR: Investigation of the relationship of spindle activity to psychosocial stress response and coping strategies in healthy kindergarten children found total number of visually detected NREM S2 sleep spindles is elevated in children with coping involving positive, high ego-involvement; in contrast, low ego-Involvement during stress is associated with reducedtotal number of NREMS2 sleepSpindles.
Abstract: Objectives. Sleep EEG spindles are linked to efficient cortical-subcortical connectivity and intellectual abilities. The aim of the present study was to investigate the relationship of spindle activity to psychosocial stress response and coping strategies in healthy kindergarten children. Methods. In a cross-sectional study of 41 5-year old kindergarten children we examined stress-induced hypothalamic-pituitary-adrenocortical (HPA) system activity by saliva cortisol measurements and sleep regulation by sleep EEG-monitoring. Stress response was measured during the application of a standardized psychological challenge appropriate at this age. NREM S2 sleep EEG spindles were visually scored and put into relation to coping and HPA activity parameters. Results. An increased total number of NREM S2 sleep spindles correlated positively with increased high ego-involvement strategies such as “positive emotions”. By contrast, total number of NREM S2 sleep spindles correlated negatively with low ego-involvem...
22 citations
2 citations
TL;DR: In this article, an onabotulinumtoxin injection into the glabellar region was used as an adjunctive treatment of major depression within a clinical trial, and the results indicated that the intervention might improve the symptoms of depression.
1 citations