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John Case

Researcher at University UCINF

Publications -  173
Citations -  5616

John Case is an academic researcher from University UCINF. The author has contributed to research in topics: Computable function & Computational learning theory. The author has an hindex of 33, co-authored 173 publications receiving 5471 citations. Previous affiliations of John Case include Rush University Medical Center & The College of New Jersey.

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Increased knee joint loads during walking are present in subjects with knee osteoarthritis

TL;DR: The finding of a significantly greater than normal external knee adduction moment in the knee OA group lends support to the hypothesis that an increased kneeAdduction moment during gait is associated with knee Oa.
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The knee adduction moment during gait in subjects with knee osteoarthritis is more closely correlated with static alignment than radiographic disease severity, toe out angle and pain.

TL;DR: While the mechanical axis was indicative of the peak adduction moments, it only accounted for about 50% of its variation, emphasizing the need for a dynamic evaluation of the knee joint loading environment.
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Comparison of identification criteria for machine inductive inference

TL;DR: A natural ωpLω+1 hierarchy of successively more general criteria of success for inductive inference machines is described based on the size of sets of anomalies in programs synthesized by such machines.
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In vivo cyclooxygenase expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis and rats with adjuvant and streptococcal cell wall arthritis.

TL;DR: Observations suggest that, in vivo, COX expression is upregulated in inflammatory joint diseases, the level of expression is genetically controlled and is a biochemical correlate of disease severity, sustained high level up-regulation is T cell dependent, and expression is down-regulated by antiinflammatory glucocorticoids.
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Nonrandom evolution of end-stage osteoarthritis of the lower limbs

TL;DR: This characterization of end-stage lower extremity OA demonstrates that the disease evolves nonrandomly; after 1 joint is replaced, the contralateral limb is significantly more likely to show progression of OA than is the ipsilateral limb.