J
John H. Donohue
Researcher at Mayo Clinic
Publications - 200
Citations - 14793
John H. Donohue is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Survival rate & Breast cancer. The author has an hindex of 67, co-authored 198 publications receiving 14043 citations. Previous affiliations of John H. Donohue include University of Pennsylvania & University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
Efficacy of Bilateral Prophylactic Mastectomy in BRCA1 and BRCA2 Gene Mutation Carriers
Lynn C. Hartmann,Thomas A. Sellers,Daniel J. Schaid,Thomas S. Frank,Cheryl L. Soderberg,Diana L. Sitta,Marlene H. Frost,Clive S. Grant,John H. Donohue,John E. Woods,Shannon K. McDonnell,Catherine Walsh Vockley,Amie M. Deffenbaugh,Fergus J. Couch,Robert B. Jenkins +14 more
TL;DR: Prophylactic mastectomy is associated with a substantial reduction in the incidence of subsequent breast cancer not only in women identified as being at high risk on the basis of a family history of breast cancer but also in known BRCA1 or BRCa2 mutation carriers.
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Oxaliplatin, Fluorouracil, and Leucovorin for Patients With Unresectable Liver-Only Metastases From Colorectal Cancer: A North Central Cancer Treatment Group Phase II Study
Steven R. Alberts,William L. Horvath,William C. Sternfeld,Richard M. Goldberg,Michelle R. Mahoney,S. R. Dakhil,Ralph Levitt,Kendrith M. Rowland,Suresh G. Nair Md,Daniel J. Sargent,John H. Donohue +10 more
TL;DR: The data suggest that FOLFOX4 has a high response rate (complete response, partial response, or reduction) in patients with liver-only metastases from colorectal cancer, allowing for successful resection of disease in a portion of patients initially not judged to be optimally resectable.
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Long-term survival after pancreatoduodenectomy for pancreatic adenocarcinoma: is cure possible?
Thomas Schnelldorfer,Adam L. Ware,Michael G. Sarr,Thomas C. Smyrk,Lizhi Zhang,Rui Qin,Rachel E. Gullerud,John H. Donohue,David M. Nagorney,Michael B. Farnell +9 more
TL;DR: Pancreatoduodenectomy for adenocarcinoma in the head of pancreas can provide long-term survival in a subset of patients, particularly in the absence of lymph node metastasis, and one of 8 patients can achieve 10-year survival with a potential for cure.
Journal ArticleDOI
Development and validation of a prognostic nomogram for recurrence-free survival after complete surgical resection of localised primary gastrointestinal stromal tumour: a retrospective analysis
Jason S. Gold,Jason S. Gold,Mithat Gonen,Antonio Gutiérrez,Javier Martin Broto,Xavier García-del-Muro,Thomas C. Smyrk,Robert G. Maki,Samuel Singer,Murray F. Brennan,Cristina R. Antonescu,John H. Donohue,Ronald P. DeMatteo +12 more
TL;DR: The nomogram accurately predicts RFS after resection of localised primary GIST and could be used to select patients for adjuvant imatinib therapy and seemed better calibrated than predictions made with the AFIP-Miettinen system.
Journal ArticleDOI
Prospectively randomized trial of postoperative adjuvant chemotherapy in patients with high-risk colon cancer.
Michael J. O'Connell,John A. Laurie,Michael J. Kahn,R J Fitzgibbons,Charles Erlichman,Lois E. Shepherd,Charles G. Moertel,W I Kocha,R Pazdur,Harry S. Wieand,Joseph Rubin,A M Vukov,John H. Donohue,James E. Krook,A Figueredo +14 more
TL;DR: The data suggest that 5-FU plus levamisole for 6 months should not be used in clinical practice, whereas 6 months of treatment with 5-fu plus leucovorin plus lev amisole is effective.