John M. Nolan

TL;DR: The chemistry, biochemistry, biophysics, and physiology of these yellow pigments that are specifically concentrated in the macula lutea are examined through the means of high-affinity binding proteins and specialized transport and metabolic proteins where they play important roles as short-wavelength light-absorbers and localized, efficient antioxidants in a region at high risk for light-induced oxidative stress.

TL;DR: Results suggest that saturable mechanisms play a role in the retinal capture and/or stabilisation of the macular carotenoids in subjects with age-related macular degeneration.

TL;DR: The relative lack of MP seen in association with increasing age, tobacco use and family history of ARM supports the hypothesis that the enhanced risk that these variables represent for ARM may be attributable, at least in part, to a parallel deficiency of macular carotenoids.

TL;DR: A novel index, the pressure to depth (PD) ratio, is strongly predictive for IOP reduction following cataract extraction, and may prove useful in surgical decision making.

TL;DR: The findings support the theory that xanthophyll carotenoids impact on cognitive function, underscoring the need for exploration of novel, noninvasive biomarkers for cognitive vulnerability and preventive strategies.