J
John P. Shapiro
Researcher at Ohio State University
Publications - 27
Citations - 799
John P. Shapiro is an academic researcher from Ohio State University. The author has contributed to research in topics: Laser capture microdissection & Lupus nephritis. The author has an hindex of 13, co-authored 27 publications receiving 667 citations. Previous affiliations of John P. Shapiro include The Ohio State University Wexner Medical Center.
Papers
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Journal ArticleDOI
Apoptosis in C3H/10T1/2 mouse embryonic cells: evidence for internucleosomal DNA modification in the absence of double-strand cleavage.
TL;DR: The results demonstrate that ultrastructural changes within the nucleus associated with endonucleolytic degradation are linked with structural degradation at higher levels of chromatin organization and suggest that apoptosis is not dependent upon internucleosomal cleavage.
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Localization to atherosclerotic plaque and biodistribution of biochemically derivatized superparamagnetic iron oxide nanoparticles (SPIONs) contrast particles for magnetic resonance imaging (MRI)
Bryan Ronain Smith,Johannes T. Heverhagen,Michael V. Knopp,Petra Schmalbrock,John P. Shapiro,Masashi Shiomi,Nicanor I. Moldovan,Mauro Ferrari,Stephen C. Lee +8 more
TL;DR: Biological targeted superparamagnetic contrast agents can contribute to non-invasive evaluation of cardiovascular lesions by simultaneously extracting morphological and biochemical data from them.
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Detection of clinically relevant levels of protein analyte under physiologic buffer using planar field effect transistors.
TL;DR: In this paper, the authors reported detection of streptavidin and clinically relevant levels of biotinylated monokine induced by interferon γ (MIG) at physiological salt concentrations with AlGaN heterojunction field effect transistors (HFETs).
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Urinary Soluble CD163: a Novel Noninvasive Biomarker of Activity for Lupus Nephritis.
Juan M. Mejia-Vilet,Xiaolan L Zhang,Cristino Cruz,Mayra L Cano-Verduzco,John P. Shapiro,Haikady N. Nagaraja,Luis E. Morales-Buenrostro,Brad H. Rovin +7 more
TL;DR: Evaluation of urinary CD163 in patients with persistent proteinuria at 6 months improved the prediction of who would achieve complete renal response at 12 months and is a promising activity biomarker that varies over time with lupus nephritis activity and treatment.
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Interferon-γ Protects First-Trimester Decidual Cells against Aberrant Matrix Metalloproteinases 1, 3, and 9 Expression in Preeclampsia
Charles J. Lockwood,Murat Basar,Umit A. Kayisli,Ozlem Guzeloglu-Kayisli,William Murk,Jenny Wang,Nicole De Paz,John P. Shapiro,Rachel Masch,Nihan Semerci,S. Joseph Huang,Frederick Schatz +11 more
TL;DR: Because inflammation underlies PE-associated shallow EVT invasion, these results suggest that excess macrophage-derived TNF-α augments expression of M MP-1, MMP-3, and MMP -9 in decidual cells to interfere with normal stepwise EVTs invasion of the decidua.