J
John P. Sumpter
Researcher at Brunel University London
Publications - 271
Citations - 48218
John P. Sumpter is an academic researcher from Brunel University London. The author has contributed to research in topics: Vitellogenin & Trout. The author has an hindex of 101, co-authored 266 publications receiving 46184 citations. Previous affiliations of John P. Sumpter include Environment Agency & Centre for Environment, Fisheries and Aquaculture Science.
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Journal ArticleDOI
Widespread Sexual Disruption in Wild Fish
TL;DR: This paper demonstrates a high incidence of intersexuality in wild populations of riverine fish (roach; Rutilus rutilus) throughout the United Kingdom and indicates that reproductive and developmental effects do result from exposure to ambient levels of chemicals present in typical British rivers.
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Estrogenic Effects of Effluents from Sewage Treatment Works
TL;DR: The presence of vitellogenin in the plasma is indicative of estrogenic stimulation of the liver in oviparous fish, and rose rapidly and very markedly when trout were maintained in the effluent.
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Identification of Estrogenic Chemicals in STW Effluent. 1. Chemical Fractionation and in Vitro Biological Screening
TL;DR: In this article, a fractionation system combined with an in vitro assay for detecting estrogenic activity was developed in order to isolate and identify the major estrogenic chemicals present in seven sewage-treatment works (STW) effluents, receiving primarily domestic effluent, discharging into British rivers.
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Estrogenic activity of surfactants and some of their degradation products assessed using a recombinant yeast screen
TL;DR: An estrogen-inducible screen was developed in yeast in order to assess whether surfactants and their major degradation products are estrogenic, and one class of surfactant classes degrade to persistent metabolites that were weakly estrogenic.
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Vitellogenesis as a biomarker for estrogenic contamination of the aquatic environment.
John P. Sumpter,Susan Jobling +1 more
TL;DR: It is found that effluent from sewage treatment works contains a chemical, or mixture of chemicals, that induces vitellogenin synthesis in male fish maintained in the effluent, thus indicating that the effluents is estrogenic.