J
John P. Sumpter
Researcher at Brunel University London
Publications - 271
Citations - 48218
John P. Sumpter is an academic researcher from Brunel University London. The author has contributed to research in topics: Vitellogenin & Trout. The author has an hindex of 101, co-authored 266 publications receiving 46184 citations. Previous affiliations of John P. Sumpter include Environment Agency & Centre for Environment, Fisheries and Aquaculture Science.
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Journal ArticleDOI
Derivation of an Aquatic Predicted No-Effect Concentration for the Synthetic Hormone, 17α-Ethinyl Estradiol
Daniel J. Caldwell,Frank Mastrocco,Thomas H. Hutchinson,Reinhard Länge,Dagobert G. Heijerick,Colin R. Janssen,Paul D. Anderson,John P. Sumpter +7 more
TL;DR: A species sensitivity distribution was constructed using no observed effect concentrations (NOECs) for reproductive effects from 39 papers in 26 species, resulting in a median hazardous concentration at which 5% of the species tested are affected (HC5,50) of 0.35 ng/L, which is recommended as the PNEC for EE2 in surface water.
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The effects of acute and chronic stress on the levels of reproductive hormones in the plasma of mature male brown trout, Salmo trutta L.
TL;DR: Chronic confinement for 1 month caused a significant elevation of plasma cortisol but suppressed the levels of plasma testosterone and 11-ketotestosterone in sexually mature male brown trout, and an acute handling stress for 1 hr elevated blood cortisol and ACTH levels and also suppressed circulating androgens.
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The deleterious effects of cortisol implantation on reproductive function in two species of trout, Salmo trutta L and Salmo gairdneri Richardson
TL;DR: The results suggest that prolonged elevation of plasma cortisol, to levels well within physiological range, can affect a wide range of reproductive parameters in both brown and rainbow trout.
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Do cytotoxic chemotherapy drugs discharged into rivers pose a risk to the environment and human health? An overview and UK case study
Andrew C. Johnson,Monika D. Jürgens,Richard J. Williams,Klaus Kümmerer,Andreas Kortenkamp,John P. Sumpter +5 more
TL;DR: Assessing for the UK, whether the current use of cytotoxic drugs, one of the most toxic pharmaceuticals in common use, could pose a risk to aquatic organisms and to humans through water recycling finds grounds for optimism on removal of these compounds.
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Hormone changes during ovulation in the rainbow trout (Salmo gairdneri Richardson)
TL;DR: The results give the first clear picture of the interrelationships between some of the major hormones known to be involved in salmonid reproduction and provide further evidence for the important role of 17 alpha-hydroxy-20 beta-dihydroprogesterone in the processes of oocyte maturation and ovulation.