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Edwin J. Routledge

Researcher at Brunel University London

Publications -  43
Citations -  8592

Edwin J. Routledge is an academic researcher from Brunel University London. The author has contributed to research in topics: Biomphalaria glabrata & Effluent. The author has an hindex of 26, co-authored 40 publications receiving 8270 citations. Previous affiliations of Edwin J. Routledge include Centre for Environment, Fisheries and Aquaculture Science & Swiss Federal Institute of Aquatic Science and Technology.

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Journal ArticleDOI

Identification of Estrogenic Chemicals in STW Effluent. 1. Chemical Fractionation and in Vitro Biological Screening

TL;DR: In this article, a fractionation system combined with an in vitro assay for detecting estrogenic activity was developed in order to isolate and identify the major estrogenic chemicals present in seven sewage-treatment works (STW) effluents, receiving primarily domestic effluent, discharging into British rivers.
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Estrogenic activity of surfactants and some of their degradation products assessed using a recombinant yeast screen

TL;DR: An estrogen-inducible screen was developed in yeast in order to assess whether surfactants and their major degradation products are estrogenic, and one class of surfactant classes degrade to persistent metabolites that were weakly estrogenic.
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Identification of Estrogenic Chemicals in STW Effluent. 2. In Vivo Responses in Trout and Roach

TL;DR: The occurrence of certain natural and synthetic steroidal estrogens in the final effluent from STW has been demonstrated and the response of adult male and female roach following exposure to 17β-estradiol was compared to the response to the alkylphenolic xenoestrogen.
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Some Alkyl Hydroxy Benzoate Preservatives (Parabens) Are Estrogenic

TL;DR: Findings from in vitro and in vivo studies which confirm that a range of alkyl hydroxy benzoate preservatives (parabens) are weakly estrogenic are reported, suggesting that the safety in use of these chemicals should be reassessed.
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Structural Features of Alkylphenolic Chemicals Associated with Estrogenic Activity

TL;DR: The aim of this project was to identify the important structural features responsible for the estrogenic activity of AP chemicals by incubating APs with different structural features in a medium containing a previously described estrogen-inducible strain of yeast expressing the human estrogen receptor.