J
John R. Sowa
Researcher at University of Pennsylvania
Publications - 1
Citations - 77
John R. Sowa is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Denaturation (biochemistry) & Alkylation. The author has an hindex of 1, co-authored 1 publications receiving 77 citations.
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Relative reactivities for monofunctional nitrogen mustard alkylation of nucleic acid components.
Charles C. Price,G.Maurice Gaucher,Prasadarao Koneru,Rhchiro Shibakawa,John R. Sowa,Masao Yamaguchi +5 more
TL;DR: While adenine units in native DNA are unreactive, in denatured DNA they react at a rate 5 times those in poly A, which is 7-fold greater than in monomeric guanine ribosides and ribotides.