John Seibyl

TL;DR: These findings corroborate post-mortem results and support the hypothesis of a dysregulation in presynaptic dopamine function in Tourette's disorder.

TL;DR: Elevated levels of central interleukin-2 might contribute to the increased dopaminergic neurotransmission, autoimmune phenomena, and abnormal brain morphology described in some patients with schizophrenia.

TL;DR: Registration of SPECT and MR images together with calculated difference maps greatly enhances the ability to localize epileptic seizure foci using a noninvasive, inexpensive imaging procedure and data processing algorithm.

TL;DR: Findings indicate more modest elevations in striatal dopamine transporters in cocaine-abusing subjects than noted in previous postmortem reports and suggest a possible relationship between cocaine-related depression and dopamine transporter binding.

TL;DR: Nonuniform attenuation correction allowed a moderate improvement in the measurement of absolute activity in individual brain ROIs when images were analyzed as target-to-background activity ratios and showed only small differences when Parkinson's disease patients and healthy control subjects were compared using nonuniform, uniform or even no attenuation Correction.