J
John W. Daly
Researcher at National Institutes of Health
Publications - 598
Citations - 35680
John W. Daly is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Adenosine & Adenosine receptor. The author has an hindex of 96, co-authored 576 publications receiving 34948 citations. Previous affiliations of John W. Daly include Karolinska Institutet & Johns Hopkins University School of Medicine.
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Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells.
TL;DR: F Forskolin would appear to activate adenylate cyclase through a unique mechanism involving both direct activation of the enzyme and facilitation or potentiation of the modulation of enzyme activity by receptors or the guanyl nucleotide-binding subunit, or both.
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Arene oxides: a new aspect of drug metabolism.
Donald M. Jerina,John W. Daly +1 more
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Adenosine receptors and behavioral actions of methylxanthines
TL;DR: The data strongly suggest that the behavioral stimulant effects of methylxanthines involve a blockade of central adenosine receptors.
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Alkaloids from amphibian skin: a tabulation of over eight-hundred compounds.
TL;DR: Although only a few of the over 800 amphibian skin alkaloids have been detected in arthropods, putative arthropod sources for the batrachotoxins and coccinelline-like tricyclics (beetles), the pumiliotoxin (ants, mites), the decahydroquinolines, izidine, pyrrolidines, and piperidines (ants), and the spirop