J
Jonathan D. Sedgwick
Publications - 1
Citations - 4027
Jonathan D. Sedgwick is an academic researcher. The author has contributed to research in topics: Interleukin 21 & Interleukin 3. The author has an hindex of 1, co-authored 1 publications receiving 3816 citations.
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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
Claire L. Langrish,Yi Yi Chen,Wendy M. Blumenschein,Jeanine D. Mattson,Beth Basham,Jonathan D. Sedgwick,Terrill K. McClanahan,Robert A. Kastelein,Daniel J. Cua +8 more
TL;DR: Using passive transfer studies, it is confirmed that these IL-23–dependent CD4+ T cells are highly pathogenic and essential for the establishment of organ-specific inflammation associated with central nervous system autoimmunity.