J
Jonathan Gómez-Raja
Researcher at Government of Extremadura
Publications - 25
Citations - 2696
Jonathan Gómez-Raja is an academic researcher from Government of Extremadura. The author has contributed to research in topics: Psychosocial & Candida albicans. The author has an hindex of 16, co-authored 24 publications receiving 1321 citations. Previous affiliations of Jonathan Gómez-Raja include University of Extremadura & University of Minnesota.
Papers
More filters
Journal ArticleDOI
Rad51-Rad52 mediated maintenance of centromeric chromatin in Candida albicans.
TL;DR: It is shown that the replication forks stall at CEN7 in a kinetochore dependent manner and fork stalling is reduced in the absence of the homologous recombination (HR) proteins Rad51 and Rad52, which maintain centromere functioning by regulating CENP-ACaCse4 levels at the programmed stall sites of early replicating centromeres.
Journal ArticleDOI
The β-arrestin-like protein Rim8 is hyperphosphorylated and complexes with Rim21 and Rim101 to promote adaptation to neutral-alkaline pH.
TL;DR: The results reveal a novel mechanism for tightly regulating the activity of a signal transduction pathway and suggest that Rim8 is taken up into multivesicular bodies and degraded within the vacuole.
Journal ArticleDOI
Rad52 function prevents chromosome loss and truncation in Candida albicans.
Encarnación Andaluz,Alberto Bellido,Jonathan Gómez-Raja,Anna Selmecki,Kelly Bouchonville,Richard Calderone,Judith Berman,Germán Larriba +7 more
TL;DR: CIN of GLH isolates is reminiscent of genomic alterations leading to cancer in human cells, and support the mutator hypothesis in which a mutator mutation or CIN phenotype facilitate more mutations/aneuploidies.
Journal ArticleDOI
ROLE OF THE HOMOLOGOUS RECOMBINATION GENES RAD51 and RAD59 IN THE RESISTANCE OF Candida albicans TO UV LIGHT, RADIOMIMETIC AND ANTI-TUMOR COMPOUNDS AND OXIDIZING AGENTS
Fátima García-Prieto,Jonathan Gómez-Raja,Encarnación Andaluz,Richard Calderone,Germán Larriba +4 more
TL;DR: Results indicate that, as described in S. cerevisiae, RAD52 plays a more prominent role than RAD51 in the repair of DSBs in C. albicans and suggest the existence of at least two Rad52-dependent HR pathways, one dependent and one independent of Rad51.
Journal ArticleDOI
IHDIP: a controlled randomized trial to assess the security and effectiveness of the incremental hemodialysis in incident patients
Javier Deira,Miguel A. Suárez,Francisca López,Emilio García-Cabrera,Antonio Gascón,Eduardo Torregrosa,Giannina E. García,Jorge A. Huertas,José C. de la Flor,Suleya Puello,Jonathan Gómez-Raja,Jesús Grande,José L. Lerma,Carlos Corradino,Carlos G. Musso,Manuel Ramos,Jesús Martín,Carlo Basile,Francesco G. Casino +18 more
TL;DR: The objective of the present controlled randomized trial (RCT) is to determine if start HD with one sessions per week (1-Wk/HD), it is associated with better patient survival and other safety parameters, and to enable to know the number of sessions a patient should receive when starting HD, depending on his RRF.