J
Jonathan J. Magaña
Researcher at Monterrey Institute of Technology and Higher Education
Publications - 81
Citations - 991
Jonathan J. Magaña is an academic researcher from Monterrey Institute of Technology and Higher Education. The author has contributed to research in topics: Spinocerebellar ataxia & Population. The author has an hindex of 15, co-authored 69 publications receiving 678 citations. Previous affiliations of Jonathan J. Magaña include National Autonomous University of Mexico & CINVESTAV.
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Journal ArticleDOI
Spinocerebellar ataxia type 2: clinical presentation, molecular mechanisms, and therapeutic perspectives.
TL;DR: Based on previous experience with other polyglutamine disorders and considering the molecular basis of SCA2 pathogenesis, a nuclei-acid-based strategy focused on the specific silencing of the dominant disease allele that preserves the expression of the wild-type allele is highly desirable and might prevent toxic neurodegenerative sequelae.
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Nanoparticle technology for treatment of Parkinson's disease: the role of surface phenomena in reaching the brain.
Gerardo Leyva-Gómez,Hernán Cortés,Jonathan J. Magaña,Norberto Leyva-García,David Quintanar-Guerrero,Benjamín Florán +5 more
TL;DR: This review provides an overview of technical aspects in the design of brain drug delivery of nanoparticles and an analysis of surface phenomena, a key aspect in the development of functional nanoparticles for Parkinson's disease.
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Non-Ionic Surfactants for Stabilization of Polymeric Nanoparticles for Biomedical Uses.
Hernán Cortés,Héctor Hernández-Parra,Sergio A Bernal-Chávez,María L Del Prado-Audelo,Isaac H. Caballero-Florán,Isaac H. Caballero-Florán,Fabiola V. Borbolla-Jiménez,Maykel González-Torres,Jonathan J. Magaña,Gerardo Leyva-Gómez +9 more
TL;DR: In this paper, the authors present an analysis of the three principal non-ionic surfactants utilized in the manufacture of polymeric nanoparticles; polysorbates, poly(vinyl alcohol), and poloxamers.
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Perspectives on gene therapy in myotonic dystrophy type 1
TL;DR: This Mini‐Review is focused on the experimental advances obtained in cell‐based and animal models toward the development of therapeutic treatments against DM1, providing a discussion of their potential application in clinical trials.
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Development and Evaluation of Alginate Membranes with Curcumin-Loaded Nanoparticles for Potential Wound-Healing Applications
Mónica C. Guadarrama-Acevedo,Raisa A. Mendoza-Flores,María L Del Prado-Audelo,Zaida Urbán-Morlán,David M Giraldo-Gomez,Jonathan J. Magaña,Maykel González-Torres,Octavio D Reyes-Hernández,Gabriela Figueroa-González,Isaac H. Caballero-Florán,Isaac H. Caballero-Florán,Carla D. Florán-Hernández,Benjamín Florán,Hernán Cortés,Gerardo Leyva-Gómez +14 more
TL;DR: A novel biodegradable wound dressing was developed by means of alginate membrane and polycaprolactone nanoparticles loaded with curcumin for potential use in wound healing, decreasing the patient’s discomfort and the risk of altering the formation of the new epithelium.