Jörg Teske

TL;DR: Observations on the elimination kinetics and the long-term detection of synthetic cannabinoids in humans suggest the possibility that synthetic cannabinoids may be extensively dis-tributed into deeper compartments, hence lead-ing to an extended window of detection due to redistribution of these substances into the bloodstream, especially following heavy consumption.

TL;DR: The VPA LC-MS/MS analysis in human serum on the basis of two mass transitions possible is an interesting alternative for the VPA pseudo multiple reaction monitoring methods (mass transition 143/143) and a proof that the developed strategy is also useful for the analysis of compounds which do not produce any stable ion fragments detectable by tandem mass spectrometry.

TL;DR: An LC–MS/MS based screening method for cannabinoids, opiates, amphetamines, cocaine, benzodiazepines and methadone was developed and demonstrated that it fulfils the recommendations for qualitative screening methods and can be applied successfully in the analysis of real samples.

TL;DR: The presented study shows that the fragmentation of GHB sodium acetate adducts is an effective way of quantification of this small molecule and is an interesting alternative to other methods based on the detection of ions smaller than 85 Da.