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Jose A. Santiago

Researcher at Sam Houston State University

Publications -  84
Citations -  1549

Jose A. Santiago is an academic researcher from Sam Houston State University. The author has contributed to research in topics: Disease & Parkinson's disease. The author has an hindex of 18, co-authored 73 publications receiving 1193 citations. Previous affiliations of Jose A. Santiago include Complutense University of Madrid & University of Los Andes.

Papers
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Shared dysregulated pathways lead to Parkinson's disease and diabetes

TL;DR: The studies that have addressed the relationship between Parkinson's disease and diabetes are summarized and it is proposed that disruptions in these shared molecular networks lead to both chronic diseases.
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The emerging role of nutrition in Parkinson's disease

TL;DR: A review of studies that have addressed the role nutrition plays in both neuroprotection and neurodegeneration in Parkinson's disease and describes in detail the nutrients and their putative mechanisms of action in PD.
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Network-based metaanalysis identifies HNF4A and PTBP1 as longitudinally dynamic biomarkers for Parkinson’s disease

TL;DR: The inverse regulation of HNF4A and PTBP1 provides a molecular rationale for the altered insulin signaling observed in PD patients and may enable novel therapeutic strategies, and may be useful for monitoring disease-modifying therapies for PD.
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System-based approaches to decode the molecular links in Parkinson's disease and diabetes.

TL;DR: The current experimental approaches to dissect the mechanisms underlying the association between PD and T2DM are contextualized and the existing challenges toward the understanding of the coexistence of these devastating aging diseases are discussed.
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The Impact of Disease Comorbidities in Alzheimer's Disease.

TL;DR: In this paper, the impact of the most common comorbidities in the clinical management of Alzheimer's disease patients is discussed, and some drugs commonly prescribed to patients with diabetes and cardiovascular disease have shown promising results in AD patients.