J
José E. García-Arrarás
Researcher at University of Puerto Rico, Río Piedras
Publications - 102
Citations - 2944
José E. García-Arrarás is an academic researcher from University of Puerto Rico, Río Piedras. The author has contributed to research in topics: Regeneration (biology) & Nervous system. The author has an hindex of 32, co-authored 97 publications receiving 2593 citations. Previous affiliations of José E. García-Arrarás include University of Puerto Rico.
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Journal ArticleDOI
Cellular mechanisms of intestine regeneration in the sea cucumber, Holothuria glaberrima Selenka (Holothuroidea:Echinodermata)
José E. García-Arrarás,Lourdes Estrada-Rodgers,Roberto Santiago,Irma I. Torres,Lucy Díaz-Miranda,Ilia Torres-Avillán +5 more
TL;DR: This study provides evidence that the process of new organ formation in holothurians can be described as an intermediate process showing characteristics of both epimorphic and morphallactic phenomena.
Journal ArticleDOI
Analysis of mice carrying targeted mutations of the glucocorticoid receptor gene argues against an essential role of glucocorticoid signalling for generating adrenal chromaffin cells.
Susetta Finotto,Kerstin Krieglstein,Andreas Schober,Frauke Deimling,Karin Lindner,Barbara Brühl,Konstantin Beier,Jürgen Metz,José E. García-Arrarás,José L. Roig-López,Paula Monaghan,Wolfgang Schmid,Timothy J. Cole,Christoph Kellendonk,Francois Tronche,Günther Schütz,Klaus Unsicker +16 more
TL;DR: It is concluded that important phenotypic features of chromaffin cells that distinguish them from sympathetic neurones develop normally in the absence of GR-mediated signalling, suggesting that the dogma of an essential role of glucocorticoid signalling for the development of chromAffin cells must be abandoned.
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Extracellular matrix remodeling and metalloproteinase involvement during intestine regeneration in the sea cucumber Holothuria glaberrima.
TL;DR: It is shown that significant changes in ECM content occur during intestine regeneration in the sea cucumber and that the onset of these changes is correlated to the proteolytic activities of MMPs.
Journal ArticleDOI
Visceral regeneration in holothurians.
TL;DR: Focusing mainly on the digestive tube, regeneration from a cellular perspective is analyzed, considering especially the origin, migration, and proliferation of the cellular components of the regenerated organ.
Journal ArticleDOI
Gene expression profiling of intestinal regeneration in the sea cucumber
Pablo Ortiz-Pineda,Francisco Ramírez-Gómez,Judit Pérez-Ortiz,Sebastián González-Díaz,Francisco Santiago-De Jesús,Josué Hernández-Pasos,Cristina Del Valle-Avila,Carmencita Rojas-Cartagena,Edna C. Suárez-Castillo,Karen Tossas,Ana T. Méndez-Merced,José L. Roig-López,Humberto Ortiz-Zuazaga,José E. García-Arrarás +13 more
TL;DR: The expression profile of animals at three different intestinal regeneration stages (3, 7- and 14-days post evisceration) is compared against the profile from normal (uneviscerated) intestines to set the base for future studies into the molecular basis of intestinal regeneration.