J
Jose E. Tanus-Santos
Researcher at University of São Paulo
Publications - 405
Citations - 13625
Jose E. Tanus-Santos is an academic researcher from University of São Paulo. The author has contributed to research in topics: Nitric oxide & Nitrite. The author has an hindex of 55, co-authored 396 publications receiving 12424 citations. Previous affiliations of Jose E. Tanus-Santos include Georgetown University Medical Center & State University of Campinas.
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Journal ArticleDOI
Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease.
Christopher D. Reiter,Xunde Wang,Jose E. Tanus-Santos,Neil Hogg,Richard O. Cannon,Alan N. Schechter,Mark T. Gladwin +6 more
TL;DR: It is demonstrated here that plasma from patients with sickle-cell disease contains cell-free ferrous hemoglobin, which stoichiometrically consumes micromolar quantities of nitric oxide and abrogates forearm blood flow responses to Nitric oxide donor infusions.
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A critical review of biomarkers used for monitoring human exposure to lead: advantages, limitations, and future needs
TL;DR: Traditional analytical protocols in current use are presented, and the influence of confounding variables on BPb levels are assessed and the significance of Pb determinations in human specimens including hair, nails, saliva, bone, blood, urine, feces, and exfoliated teeth are discussed.
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Effects of ethnicity on the distribution of clinically relevant endothelial nitric oxide variants.
TL;DR: The marked interethnic differences that are found in the distribution of eNOS variants, in the estimated haplotype frequency, and in the association between variants may help to understand how the combination of these genetic variants may influence cardiovascular diseases.
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Metalloproteinase inhibition ameliorates hypertension and prevents vascular dysfunction and remodeling in renovascular hypertensive rats.
Michele M. Castro,Elen Rizzi,Lívia Figueiredo-Lopes,Karla Fernandes,Lusiane M. Bendhack,Dimitrius Leonardo Pitol,Raquel F. Gerlach,Jose E. Tanus-Santos +7 more
TL;DR: It is suggested that MMP-2 plays a role in 2K-1C hypertension and its structural and functional vascular changes, which were attenuated by doxycycline.
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Nitric oxide formation is inversely related to serum levels of antiangiogenic factors soluble fms-like tyrosine kinase-1 and soluble endogline in preeclampsia.
Valeria C. Sandrim,Ana C. Palei,Ingrid F. Metzger,Valeria A. Gomes,Ricardo de Carvalho Cavalli,Jose E. Tanus-Santos +5 more
TL;DR: The negative correlations between markers of NO formation and antiangiogenic factors in preeclamptic patients suggest an inhibitory effect for these factors on NO formation, and clinical evidence for impaired NO formation is shown.