J
Josef Briegel
Researcher at Ludwig Maximilian University of Munich
Publications - 229
Citations - 13909
Josef Briegel is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Septic shock & Intensive care. The author has an hindex of 51, co-authored 215 publications receiving 12691 citations.
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Journal ArticleDOI
Hydrocortisone Therapy for Patients with Septic Shock
Charles L. Sprung,Djillali Annane,Didier Keh,Rui Moreno,Mervyn Singer,Klaus Freivogel,Yoram Weiss,Julie Benbenishty,Armin Kalenka,Helmuth Forst,Pierre-François Laterre,Konrad Reinhart,Brian H Cuthbertson,Didier Payen,Josef Briegel,Klinikum Mannheim +15 more
TL;DR: Hydrocortisone did not improve survival or reversal of shock in patients with septic shock, either overall or in patients who did not have a response to corticotropin, although hydroc Cortisone hastened reversal ofshock in patients in whom shock was reversed.
Journal ArticleDOI
Stress doses of hydrocortisone reverse hyperdynamic septic shock: a prospective, randomized, double-blind, single-center study.
Josef Briegel,Helmuth Forst,Mathias Haller,Gustav Schelling,Erich Kilger,Gerrit Kuprat,Barbara Hemmer,T. Hummel,Andreas Lenhart,Mathias Heyduck,Christian Stoll,Klaus Peter +11 more
TL;DR: Infusion of stress doses of hydrocortisone reduced the time to cessation of vasopressor therapy in human septic shock and was associated with a trend to earlier resolution of sepsis-induced organ dysfunctions.
Journal ArticleDOI
Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine.
Paul E. Marik,Stephen M. Pastores,Djillali Annane,Gianfranco Umberto Meduri,Charles L. Sprung,Wiebke Arlt,Didier Keh,Josef Briegel,Albertus Beishuizen,Ioanna Dimopoulou,Stylianos Tsagarakis,Mervyn Singer,George P. Chrousos,Gary P. Zaloga,Faran Bokhari,Michael Vogeser +15 more
TL;DR: In this paper, a multidisciplinary, multispecialty task force of experts in critical care medicine was convened from the membership of the Society of Critical Car to develop consensus statements for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients.
Journal ArticleDOI
Health-related quality of life and posttraumatic stress disorder in survivors of the acute respiratory distress syndrome
Gustav Schelling,Christian Stoll,Michael J. Haller,Josef Briegel,W. Manert,T. Hummel,Andreas Lenhart,M Heyduck,Jan Polasek,M. Meier,U Preuss,M. Bullinger,W. Schuffel,Klaus Peter +13 more
TL;DR: Survivors of ARDS showed statistically significant impairments in all eight health dimensions of the SF-36 when compared with normal controls, and patients reporting multiple adverse experiences described the lowest health-related quality of life.
Journal ArticleDOI
Corticosteroids in the treatment of severe sepsis and septic shock in adults: a systematic review.
Djillali Annane,Eric Bellissant,Pierre Edouard Bollaert,Josef Briegel,Marco Confalonieri,Raffaele De Gaudio,Didier Keh,Yizhak Kupfer,Michael Oppert,G. Umberto Meduri +9 more
TL;DR: The benefits and risks of corticosteroid treatment in severe sepsis and septic shock and the influence of dose and duration are examined and analysis of this subgroup suggests a beneficial drug effect on short-term mortality.