J
Joseph M. Martel
Researcher at Harvard University
Publications - 15
Citations - 2119
Joseph M. Martel is an academic researcher from Harvard University. The author has contributed to research in topics: Whole blood & Chemotaxis. The author has an hindex of 14, co-authored 15 publications receiving 1819 citations. Previous affiliations of Joseph M. Martel include VA Boston Healthcare System.
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Journal ArticleDOI
Microfluidic, marker-free isolation of circulating tumor cells from blood samples
Nezihi Murat Karabacak,Philipp S. Spuhler,Fabio Fachin,Eugene J. Lim,Vincent Pai,Emre Ozkumur,Joseph M. Martel,Nikola Kojic,Kyle C. Smith,Pin-i Chen,Jennifer Yang,Henry H. Hwang,Bailey Morgan,Julie Trautwein,Tom Barber,Shannon L. Stott,Shyamala Maheswaran,Ravi Kapur,Daniel A. Haber,Mehmet Toner +19 more
TL;DR: The procedure for isolating rare CTCs from blood samples by using tumor antigen–independent microfluidic CTC-iChip technology, which uses deterministic lateral displacement, inertial focusing and magnetophoresis to sort up to 107 cells/s.
Journal ArticleDOI
Inertial Focusing in Microfluidics
Joseph M. Martel,Mehmet Toner +1 more
TL;DR: The theoretical developments that have made the field of inertial focusing what it is today are described and the key applications that will make inertialocusing a mainstream technology in the future are presented.
Journal ArticleDOI
Inertial focusing dynamics in spiral microchannels
Joseph M. Martel,Mehmet Toner +1 more
TL;DR: A continuum of particle streak behavior is shown with longitudinal, cross-sectional, and velocity resolution, yielding a large analyzed parameter space in low aspect ratio spiral microchannel designs.
Journal ArticleDOI
Particle Focusing in Curved Microfluidic Channels
Joseph M. Martel,Mehmet Toner +1 more
TL;DR: In this article, a complex set of inertial focusing behavioral regimes are discovered within curved microfluidic channels over a range of channel Reynolds numbers, curvature ratios and particle confinement ratios.
Journal ArticleDOI
Tunable nanostructured coating for the capture and selective release of viable circulating tumor cells.
Eduardo Reátegui,Nicola Aceto,Eugene J. Lim,Eugene J. Lim,James P. Sullivan,Anne E. Jensen,Mahnaz Zeinali,Joseph M. Martel,Alexander J. Aranyosi,Wei Li,Steven A. Castleberry,Aditya Bardia,Lecia V. Sequist,Daniel A. Haber,Daniel A. Haber,Shyamala Maheswaran,Paula T. Hammond,Mehmet Toner,Shannon L. Stott +18 more
TL;DR: A layer-by-layer gelatin nanocoating is presented for use as a tunable, dual response biomaterial for the capture and release of circulating tumor cells (CTCs) from cancer patient blood.