JS Shah

TL;DR: An unexpectedly high percentage of patients with heart failure fulfilling current echocardiographic criteria for LVNC is demonstrated, which might be explained by a hitherto underestimated cause of heart failure, but the comparison with controls suggests that current diagnostic criteria are too sensitive, particularly in black individuals.

TL;DR: LVOTO is associated with an increased risk of SD/ICD that is related to the severity of obstruction and the presence of other recognized risk factors for SD, and the low sudden death mortality in asymptomatic patients with LVOTO and no other SD risk markers suggests that aggressive interventions to reduce LVOTO are unwarranted in this group.

TL;DR: Enzyme replacement therapy with agalsidase alfa resulted in regression of the hypertrophic cardiomyopathy associated with Anderson–Fabry disease.

TL;DR: In this article, the authors compared and contrasted the natural history of a cohort of patients seen between 1988 and 2002 with that of other published series, and determined the range of survival rates of patients with hypertrophic cardiomyopathy.

TL;DR: Arrhythmias are common in older patients with AFD, and the high incidence of pacemaker implantation and sudden cardiac death suggests that arrhythmia has a significant impact on the natural history of AFD.