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Ju-Tao Chen

Researcher at University of Science and Technology of China

Publications -  41
Citations -  1235

Ju-Tao Chen is an academic researcher from University of Science and Technology of China. The author has contributed to research in topics: Long-term potentiation & Synaptic plasticity. The author has an hindex of 20, co-authored 41 publications receiving 1153 citations. Previous affiliations of Ju-Tao Chen include Singapore General Hospital.

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Unmodified CdSe quantum dots induce elevation of cytoplasmic calcium levels and impairment of functional properties of sodium channels in rat primary cultured hippocampal neurons.

TL;DR: Investigating the potential for neurotoxicity of cadmium selenium QDs in a hippocampal neuronal culture model found that QDs induced neuron death dose dependently and new insights into QD toxicology are provided.
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Local infusion of ghrelin enhanced hippocampal synaptic plasticity and spatial memory through activation of phosphoinositide 3-kinase in the dentate gyrus of adult rats

TL;DR: It is proposed that the ghrelin signaling pathway could have therapeutic value in cognitive deficits after a single infusion into the hippocampus led to long‐lasting potentiation of excitatory postsynaptic potentials and population spikes in the dentate gyrus of anesthetized rats.
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Effects of developmental exposure to TiO2 nanoparticles on synaptic plasticity in hippocampal dentate gyrus area: an in vivo study in anesthetized rats.

TL;DR: The findings suggest that developmental exposure to TiO2 NPs could affect synaptic plasticity in offspring’s hippocampal DG area in vivo, which indicates that developmental brains, especially in lactation, are susceptible toTiO1 NPs exposure.
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Impairment of long-term potentiation and paired-pulse facilitation in rat hippocampal dentate gyrus following developmental lead exposure in vivo

TL;DR: The results suggested that developmental lead exposure in neonatal rats caused impairments in long-term potentiation and paired-pulse facilitation of hippocampal dentate gyrus in adult rats, and more serious than that of EPSP potentiation.
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JNK1 contributes to metabotropic glutamate receptor-dependent long-term depression and short-term synaptic plasticity in the mice area hippocampal CA1.

TL;DR: It is shown that short‐term synaptic plasticity was impaired in the hippocampal area CA1 of JNK1‐deficient mice; these mice showed normal LTP in response to a strong tetanus and no alteration of N‐methyl‐d‐aspartate receptor‐dependent long‐term depression in the hippocampus.