J
Juan José Madrigal-Sánchez
Researcher at University of Costa Rica
Publications - 11
Citations - 28
Juan José Madrigal-Sánchez is an academic researcher from University of Costa Rica. The author has contributed to research in topics: Population & Haplotype. The author has an hindex of 3, co-authored 10 publications receiving 22 citations.
Papers
More filters
Journal ArticleDOI
High-resolution HLA allele and haplotype frequencies in majority and minority populations of Costa Rica and Nicaragua: Differential admixture proportions in neighboring countries.
Esteban Arrieta-Bolaños,Esteban Arrieta-Bolaños,Juan José Madrigal-Sánchez,Jeremy E. Stein,Priscilla Órlich-Pérez,M. J. Moreira-Espinoza,E. Paredes-Carias,Y. Vanegas-Padilla,Lizbeth Salazar-Sánchez,JA Madrigal,JA Madrigal,S. G. E. Marsh,S. G. E. Marsh,Bronwen E. Shaw,Bronwen E. Shaw +14 more
TL;DR: This is the first comprehensive study reporting high‐resolution HLA diversity in Central America, and its results will shed light into the genetic history of this region while also supporting the development of medical programs for organ and stem cell transplantation.
Journal ArticleDOI
4-Locus high-resolution HLA allele and haplotype frequencies in Costa Ricans from African-Caribbean descent.
Esteban Arrieta-Bolaños,Esteban Arrieta-Bolaños,Juan José Madrigal-Sánchez,Jeremy E. Stein,Gilbert Arrieta-Molina,Sonia Grant,Lizbeth Salazar-Sánchez,J. Alejandro Madrigal,Steven G.E. Marsh,Bronwen E. Shaw +9 more
TL;DR: A total of 102 Costa Ricans of African-Caribbean descent were genotyped at high-resolution for the human leukocyte antigen loci HLA-A, -B, -C, and -DRB1 using sequence-based typing methods, finding no deviation from Hardy-Weinberg Equilibrium at any of the loci studied.
Journal ArticleDOI
A novel HLA-A allele, A*74:23, identified in an individual from Costa Rica.
Esteban Arrieta-Bolaños,Esteban Arrieta-Bolaños,Esteban Arrieta-Bolaños,A.J. McWhinnie,Juan José Madrigal-Sánchez,L. Calvo,Lizbeth Salazar-Sánchez,JA Madrigal,JA Madrigal,S. G. E. Marsh,S. G. E. Marsh,Bronwen E. Shaw,Bronwen E. Shaw +12 more
TL;DR: The new HLA-A* 74:23 allele differs from the closest allele A*74:01 by a nucleotide change in exon 3 at codon 97.
Book ChapterDOI
ACE I/D (Rs1799752), MTHFR C677T (Rs1801133), and CCR5 D32 (Rs333) Genes and their Association with Hypertension and Diabetic Nephropathy in Urban Areas of Costa Rica, Nicaragua, and Mexico
Lizbeth Salazar-Sánchez,Juan José Madrigal-Sánchez,PedroGonzalez-Martinez,Edel Paredes,Ligia Vera-Gamboa,Norma Pavía-Ruz,Nina Valadez-González +6 more
TL;DR: It is important to know the role of ACE and CCR5 molecular markers and their possible association with the development of microvascular complications in the authors' populations, as well as to investigate the prevalence in thrombotic markers that lead to hypercoagulability and its association with hypertension and diabetic nephropathy.
Journal ArticleDOI
4-Locus high-resolution HLA allele and haplotype frequencies in Costa Ricans from Guanacaste.
Esteban Arrieta-Bolaños,Esteban Arrieta-Bolaños,Juan José Madrigal-Sánchez,Jeremy E. Stein,Gilbert Arrieta-Molina,Lizbeth Salazar-Sánchez,J. Alejandro Madrigal,Steven G.E. Marsh,Bronwen E. Shaw +8 more
TL;DR: A total of 110 Costa Rican Mestizos from the province of Guanacaste were genotyped at high-resolution for the human leukocyte antigen loci HLA-A, -B, -C, and -DRB1 using sequence-based typing methods, and the respective allele and extended haplotype frequencies, as well as Hardy-Weinberg proportions were calculated.