Journal•ISSN: 0198-8859
Human Immunology
Elsevier BV
About: Human Immunology is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Human leukocyte antigen & Antigen. It has an ISSN identifier of 0198-8859. Over the lifetime, 6615 publications have been published receiving 155275 citations.
Topics: Human leukocyte antigen, Antigen, Population, Haplotype, Transplantation
Papers published on a yearly basis
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TL;DR: A novel single nucleotide polymorphism, T to A, at the 5' end of the CA repeat region in the first intron of the human IFN-gamma gene (+874*T/A) is reported, which could directly influence the level ofIFN-Gamma production associated with the CA microsatellite marker.
610 citations
TL;DR: The results underline the primary importance of HLA-DQ alleles in susceptibility to celiac disease, and the extreme rarity of celiac patients carrying neither the D Q2 or DQ8 heterodimers nor one half of the DQ2 heterodimer alone.
575 citations
TL;DR: Differences in both LD and heterozygosity levels suggest distinct evolutionary histories of the HLA loci in the geographical regions from where the U.S. populations originated.
456 citations
TL;DR: The results indicate that FOXP3 expression in humans, unlike mice, may not be specific for cells with a regulatory phenotype and may be only a consequence of activation status.
446 citations
TL;DR: The sphinx of immunology, the major histocompatibility complex (MHC), has revealed most of her secrets except the two most profound ones: what is the true MHC function, andWhat is the origin and significance of MHC polymorphism?
443 citations