J
Juan P. Cata
Researcher at University of Texas MD Anderson Cancer Center
Publications - 210
Citations - 5143
Juan P. Cata is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Perioperative & Medicine. The author has an hindex of 35, co-authored 170 publications receiving 3978 citations. Previous affiliations of Juan P. Cata include Outcomes Research Consortium.
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Taxol-induced sensory disturbance is characterized by preferential impairment of myelinated fiber function in cancer patients.
TL;DR: The data suggest that taxol produces a neuropathy characterized by pronounced impairment of function in A‐beta myelination fibers, intermediate impairment of A‐delta myelinated fibers, and a relative sparing of C‐fibers.
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The Cancer Chemotherapeutic Paclitaxel Increases Human and Rodent Sensory Neuron Responses to TRPV1 by Activation of TLR4
Yan Li,Pavel Adamek,Haijun Zhang,Claudio E. Tatsui,Laurence D. Rhines,Petra Mrozkova,Qin Li,Alyssa K. Kosturakis,Ryan M. Cassidy,Daniel S. Harrison,Juan P. Cata,Kenneth Sapire,Hongmei Zhang,Ross M. Kennamer-Chapman,Abdul Basit Jawad,Andrea Ghetti,Jiusheng Yan,Jiri Palecek,Patrick M. Dougherty +18 more
TL;DR: It is shown for the first time that paclitaxel activates peripheral sensory and spinal neurons directly and sensitizes these cells to transient receptor potential vanilloid subtype 1 (TRPV1)-mediated capsaicin responses via Toll-like receptor 4 (TLR4) in multiple species.
Journal Article
Clinical and experimental findings in humans and animals with chemotherapy-induced peripheral neuropathy.
TL;DR: Clinical and laboratory findings on the characteristics of chemotherapy-induced neuropathic pain are reviewed and a scheme for the underlying mechanisms is outlined.
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Quantitative Sensory Findings in Patients With Bortezomib-Induced Pain
Juan P. Cata,Han-Rong Weng,Allen W. Burton,Horatio Villareal,Sergio Giralt,Patrick M. Dougherty +5 more
TL;DR: It is shown that patients with bortezomib-induced neuropathic pain have significantly elevated touch detection threshold and slotted peg board time, impaired sharpness detection, and elevated thresholds for the detection of skin warming and heat pain.
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Posterior Intercostal Nerve Block With Liposomal Bupivacaine: An Alternative to Thoracic Epidural Analgesia
David C. Rice,Juan P. Cata,Gabriel E. Mena,Andrea Rodriguez-Restrepo,Arlene M. Correa,Reza J. Mehran +5 more
TL;DR: Posterior intercostal nerve blockade using LipoB is safe and provides effective analgesia for patients undergoing thoracic surgery and may be considered as a suitable alternative to TEA.