Judith D. Brown

TL;DR: This review will examine both classical and current models of chromosomal speciation and describe the "evolving" theory of genetic conflict, epigenetics, and chromosomal Speciation.

TL;DR: Genome-wide analyses suggest that common neuronal pathways may be disrupted in both the Angelman and Dup15q syndromes, and chromatin structure may influence gene expression across the 15q11-q13.1 region in neurons.

TL;DR: The Sry transgene in FCG mice is present in multiple copies at one locus on chromosome 3, which does not interrupt known genes, suggesting that differences between XX and XY mice with the same type of gonad are not caused by difference in prenatal androgen levels.

TL;DR: Recent evidence that ncRNAs can facilitate chromosome change is summarized and mechanisms by which nc RNAs create DNA breaks are presented, which present hypotheses on how they may create novel karyotypes and thus affect chromosome evolution.

TL;DR: The high rate of engraftment, the similarity to the high-grade malignant glioma of origin, and the rapid, locally invasive growth of these tumors should make this murine model useful in testing novel therapies for human malignantgliomas.