J
Juhwan Kim
Researcher at Chonnam National University
Publications - 30
Citations - 771
Juhwan Kim is an academic researcher from Chonnam National University. The author has contributed to research in topics: Hippocampal formation & Hippocampus. The author has an hindex of 15, co-authored 28 publications receiving 600 citations. Previous affiliations of Juhwan Kim include Korea Institute of Science and Technology & University of Connecticut.
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Journal ArticleDOI
Brain Reward Circuits in Morphine Addiction.
TL;DR: This review highlights recent findings on the roles of several reward circuits involved in morphine addiction based on pharmacological, molecular and physiological evidences.
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Hippocampal dysfunctions in tumor-bearing mice
Miyoung Yang,Miyoung Yang,Juhwan Kim,Joong Sun Kim,Sung-Ho Kim,Jong-Choon Kim,Man Jong Kang,Uhee Jung,Taekyun Shin,Hongbing Wang,Changjong Moon +10 more
TL;DR: A peripheral tumor alone may be sufficient to induce hippocampal dysfunction, possibly by reducing the rate of neurogenesis and the levels of BDNF and COX-2 in that tissue and also by increasing stress-related parameters and the circulating levels of pro-inflammatory cytokines.
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Acute treatment with methotrexate induces hippocampal dysfunction in a mouse model of breast cancer
Miyoung Yang,Joong Sun Kim,Juhwan Kim,Sungwoong Jang,Sung-Ho Kim,Jong-Choon Kim,Taekyun Shin,Hongbing Wang,Changjong Moon +8 more
TL;DR: It is indicated that the acute neurotoxic effect of MTX leads to hippocampal dysfunction including depressive-like behaviors and memory deficits, which may be related to an inhibition of neurogenesis and an increase of the inflammatory response in the hippocampus of a mouse model of breast cancer.
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Neurotoxicity of methotrexate to hippocampal cells in vivo and in vitro
Miyoung Yang,Joong Sun Kim,Juhwan Kim,Sung-Ho Kim,Jong-Choon Kim,Jinwook Kim,Hongbing Wang,Taekyun Shin,Changjong Moon +8 more
TL;DR: The neurotoxic effect of MTX inhibits the proliferation of hippocampal progenitor cells and can cause hippocampal dysfunction, such as depression and cognitive impairment, which suggests that the susceptibility of such hippocampal cells depends on their maturation.
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Trimethyltin-induced hippocampal neurodegeneration: A mechanism-based review
Sueun Lee,Miyoung Yang,Jinwook Kim,Sohi Kang,Juhwan Kim,Jong-Choon Kim,Chaeyong Jung,Taekyun Shin,Sung-Ho Kim,Changjong Moon +9 more
TL;DR: This review summarizes the in vivo and in vitro underlying mechanisms of TMT-induced hippocampal neurodegeneration (oxidative stress, inflammatory responses, and neuronal death/survival) and approaches to therapeutic interventions for Neurodegenerative diseases, including temporal lobe epilepsy.