J
Julia F. Keller
Publications - 1
Citations - 55
Julia F. Keller is an academic researcher. The author has contributed to research in topics: Janus kinase 1 & Cytoplasm. The author has an hindex of 1, co-authored 1 publications receiving 47 citations.
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Multiple reasons for an inefficient STAT1 response upon IL-6-type cytokine stimulation.
TL;DR: It is found that IL-6-type cytokine stimulation of cell lines and primary human macrophages results in a different distribution of the DNA-binding competent STAT dimer species in the cytosol and nucleus as demonstrated by electrophoretic mobility shift assays and that pY-STAT3 is much more efficiently shuttled into the nucleus than py-STAT1.