Journal•ISSN: 0898-6568
Cellular Signalling
Elsevier BV
About: Cellular Signalling is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Signal transduction & Phosphorylation. It has an ISSN identifier of 0898-6568. Over the lifetime, 5946 publications have been published receiving 236300 citations.
Topics: Signal transduction, Phosphorylation, Kinase, Receptor, MAPK/ERK pathway
Papers published on a yearly basis
Papers
More filters
TL;DR: This review focuses on the molecular mechanisms through which ROS directly interact with critical signaling molecules to initiate signaling in a broad variety of cellular processes, such as proliferation and survival, ROS homeostasis and antioxidant gene regulation, mitochondrial oxidative stress, apoptosis, and aging.
3,372 citations
TL;DR: This work has elucidated how LPS is recognized by monocytes and macrophages of the innate immune system and activates a variety of transcription factors that include NF-kappaB (p50/p65) and AP-1 (c-Fos/c-Jun), which coordinate the induction of many genes encoding inflammatory mediators.
2,269 citations
TL;DR: Recent developments in understanding the mechanisms and consequences of PKB/Akt activation in human malignancy are surveyed.
1,626 citations
TL;DR: The characteristics of the major components of the p38 signalling transduction pathway are summarized and the targets of this pathway are highlighted and the physiological function ofThe p38 activation is highlighted.
1,579 citations
TL;DR: This review summarizes current studies that have been regarding the production of ROS and the general redox-sensitive targets of cell signalling cascades.
1,121 citations