J
Julia Fernández-Pérez
Researcher at Trinity College, Dublin
Publications - 18
Citations - 442
Julia Fernández-Pérez is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Decellularization & Transplantation. The author has an hindex of 7, co-authored 16 publications receiving 202 citations. Previous affiliations of Julia Fernández-Pérez include Maastricht University & Leibniz Association.
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Journal ArticleDOI
The impact of decellularization methods on extracellular matrix derived hydrogels.
TL;DR: The aim of this study was to examine the impact of decellularization protocols in ECM-derived hydrogels obtained from porcine corneas and found that freeze-thaw de cellularization produced Hydrogels with the overall best properties.
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Designing Scaffolds for Corneal Regeneration
TL;DR: Recent advancements in materials fabrication techniques such as bioprinting, electrospinning, and different collagen alignment techniques, allow scaffolds to be generated that more accurately mimic the structure of the corneal stroma.
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Characterization of extracellular matrix modified poly(ε-caprolactone) electrospun scaffolds with differing fiber orientations for corneal stroma regeneration
TL;DR: Aligned scaffolds with incorporated ECM show promise for their use as cell-free implants that promote endogenous repopulation by neighboring cells that reduce the need for donor cornea transplantation based on tissue engineering.
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Decellularization and recellularization of cornea: Progress towards a donor alternative.
TL;DR: Different decellularization techniques are described, including physical, chemical and biological methods, which aim to remove cells from organs or tissues resulting in a cell-free scaffold consisting of the tissues extracellular matrix.
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Influence of Biochemical Cues in Human Corneal Stromal Cell Phenotype
TL;DR: Partially recovery towards a quiescent keratocyte-like phenotype was achieved by the removal of serum and the addition of AA, IGF-1, RA, ITS and IBMX to a basal medium, which can be used to develop cell-based corneal therapies and to study cornea diseases in vitro.