J
Julian Sommer
Researcher at Goethe University Frankfurt
Publications - 7
Citations - 88
Julian Sommer is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Plasmid & Acinetobacter calcoaceticus. The author has an hindex of 3, co-authored 6 publications receiving 46 citations.
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Journal ArticleDOI
Comparison of Phenotypic Tests and an Immunochromatographic Assay and Development of a New Algorithm for Detection of OXA-48-like Carbapenemases
Florian Koroska,Stephan Göttig,Martin Kaase,Jörg Steinmann,Sören Gatermann,Julian Sommer,Thorsten Wille,Georg Plum,Axel Hamprecht +8 more
TL;DR: A new algorithm incorporating temocillin, faropenem, and ICT which allows cost-effective detection of OXA-48 with 100% sensitivity and specificity was developed and was found to be more costly than phenotypic assays.
Journal ArticleDOI
Pathogenicity of Clinical OXA-48 Isolates and Impact of the OXA-48 IncL Plasmid on Virulence and Bacterial Fitness.
Axel Hamprecht,Julian Sommer,Matthias Willmann,Christina Brender,Yvonne Stelzer,Felix F. Krause,Tsvetan Tsvetkov,Florian Wild,Sara Riedel-Christ,Julia Kutschenreuter,Can Imirzalioglu,Aitor Gonzaga,Ulrich Nübel,Ulrich Nübel,Stephan Göttig +14 more
TL;DR: It is demonstrated that this 63 kb IncL plasmid has a low fitness burden, high plasmids stability and can be transferred by highly efficient HGT which is likely the cause of the rapid dissemination of OXA-48 rather than the expansion of a single clone or gain of virulence.
Journal ArticleDOI
Comparison of nine different selective agars for the detection of carbapenemase-producing Enterobacterales (CPE)
Stephan Göttig,Sarah V Walker,Ahmad Saleh,Florian Koroska,Julian Sommer,Yvonne Stelzer,Joerg Steinmann,Joerg Steinmann,Axel Hamprecht +8 more
TL;DR: Overall, Brilliance CRE and the McCARB in-house agars showed the best performance and were able to detect most CPE, including almost all OXA-48.
Journal ArticleDOI
OXA-484, an OXA-48-Type Carbapenem-Hydrolyzing Class D β-Lactamase From Escherichia coli.
Julian Sommer,Kristina M. Gerbracht,Felix F. Krause,Florian Wild,Manuela Tietgen,Sara Riedel-Christ,Janko Sattler,Axel Hamprecht,Volkhard A. J. Kempf,Stephan Göttig +9 more
TL;DR: In this paper, the authors investigated the so far uncharacterized carbapenemase OXA-484 from a clinical E. coli isolate belonging to the high-risk clone ST410 regarding antibiotic resistance pattern, horizontal gene transfer (HGT) and genetic support.
Journal ArticleDOI
Characterization of the novel OXA-213-like β-lactamase OXA-822 from Acinetobacter calcoaceticus
Manuela Tietgen,Laura Leukert,Julian Sommer,Jan S. Kramer,Steffen Brunst,Ilka Wittig,Ewgenij Proschak,Stephan Göttig +7 more
TL;DR: The novel OXA-822 from a clinical A. calcoaceticus isolate displayed penicillinase and carbapenemase activity in vitro, elevated MICs in different species and decreased carbAPenem susceptibility in A. baumannii in vivo.