Matthias Willmann

TL;DR: It is shown that nasal Staphylococcus lugdunensis strains produce lugdunin, a novel thiazolidine-containing cyclic peptide antibiotic that prohibits colonization by S. aureus, and a rare example of a non-ribosomally synthesized bioactive compound from human-associated bacteria.

TL;DR: The Accelerate Pheno system provided fast, reliable results while significantly improving turnaround time in blood culture diagnostics of Gram-negative BSI and compared to conventional culture-based methods in the laboratory setting.

TL;DR: The observed prevalence of 9.5% 3GCREB carriage was higher than previously reported and differed significantly among centres, and the treatment of GERD proved to be an independent risk factor for 3 GCREB colonization.

TL;DR: This study quantified changes in the gut microbiome in two cohorts of hematological patients receiving prophylactic antibiotics and found that factors such as individual baseline microbiome, resistome, and plasmid diversity; liver/kidney function; and concurrent medication, especially virostatic agents, influence resistome alterations.

TL;DR: Risk factors independently associated with XDR P. aeruginosa colonization or infections are described in four groups with reference to antimicrobial therapy, medical devices as well as patient- and hospital environment-related factors.