J
Juliana de Souza Apostólico
Researcher at Federal University of São Paulo
Publications - 23
Citations - 449
Juliana de Souza Apostólico is an academic researcher from Federal University of São Paulo. The author has contributed to research in topics: Immune system & Adjuvant. The author has an hindex of 8, co-authored 20 publications receiving 299 citations. Previous affiliations of Juliana de Souza Apostólico include University of São Paulo.
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Journal ArticleDOI
Adjuvants: Classification, Modus Operandi, and Licensing
Juliana de Souza Apostólico,Victória Alves Santos Lunardelli,Fernanda Caroline Coirada,Silvia Beatriz Boscardin,Daniela Santoro Rosa +4 more
TL;DR: The most well known adjuvants used in experimental and clinical settings are described based on their main mechanisms of action and the requirements for licensing new vaccine formulations are highlighted.
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HIV Envelope Trimer Specific Immune Response Is Influenced by Different Adjuvant Formulations and Heterologous Prime-Boost.
Juliana de Souza Apostólico,Silvia Beatriz Boscardin,Marcio Massao Yamamoto,Jethe Nunes de Oliveira-Filho,Jorge Kalil,Edecio Cunha-Neto,Daniela Santoro Rosa +6 more
TL;DR: It is shown that vaccination with gp140 in the presence of different adjuvants can induce high-affinity antibodies, follicular helper T cells and germinal center B cells and the data show that poly (I:C) is the most potent adjuvant to induce specific CMI responses evidenced by IFN-γ production and CD4+/CD8+ T cell proliferation.
Journal ArticleDOI
Sleep deprivation predisposes allergic mice to neutrophilic lung inflammation
Jethe O.F. Nunes,Juliana de Souza Apostólico,David A. G. Andrade,Francieli S. Ruiz,Edgar Ruz Fernandes,Monica L. Andersen,Alexandre C. Keller,Daniela Santoro Rosa +7 more
TL;DR: Sleep quality participates in the progression of allergen‐induced eosinophilic lung inflammation to corticosteroid‐refractory neutrophilic manifestation, and disruption of IL‐17 signaling prevented airway neutrophilia in allergic mice with SD.
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Multiple Approaches for Increasing the Immunogenicity of an Epitope-Based Anti-HIV Vaccine
Daniela Santoro Rosa,Susan Pereira Ribeiro,Simone G. Fonseca,Rafael Ribeiro Almeida,Rafael Ribeiro Almeida,Vinicius Canato Santana,Vinicius Canato Santana,Juliana de Souza Apostólico,Jorge Kalil,Edecio Cunha-Neto +9 more
TL;DR: This review of alternative strategies to increase the immunogenicity of an epitope-based vaccine against HIV infection focuses on multiepitopic DNA vaccines that induced broad and polyfunctional T cell responses in immunized mice.
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Night shift work and immune response to the meningococcal conjugate vaccine in healthy workers: a proof of concept study.
Francieli S. Ruiz,Francieli S. Ruiz,Daniela Santoro Rosa,Ioná Zalcman Zimberg,Marcus Vl. dos Santos Quaresma,Juliana de Souza Apostólico,Lily Yin Weckx,Alessandra R. Souza,Fernanda Veruska Narciso,Silvio Araújo Fernandes-Junior,Bruno S B Gonçalves,Simon Folkard,Lia Bittencourt,Sergio Tufik,Marco Túlio de Mello +14 more
TL;DR: In association with circadian components, sufficient sleep time and rhythm synchronization were important for the development of the Ag-specific immune response, suggesting that the humoral response to vaccination may be impaired in individuals with chronic sleep restriction and circadian misalignment.