J
Julie A. Jarrett
Researcher at Genentech
Publications - 3
Citations - 2853
Julie A. Jarrett is an academic researcher from Genentech. The author has contributed to research in topics: Transforming growth factor & Peptide sequence. The author has an hindex of 3, co-authored 3 publications receiving 2826 citations.
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Journal ArticleDOI
Human transforming growth factor-beta complementary DNA sequence and expression in normal and transformed cells.
Rik Derynck,Julie A. Jarrett,Ellson Y. Chen,Dennis H. Eaton,John Richard Bell,Richard K. Assoian,Anita B. Roberts,Michael B. Sporn,David V. Goeddel +8 more
TL;DR: The cDNA sequence indicates that the 112-amino acid monomeric form of the natural TGF-β homodimer is derived proteolytically from a much longer precursor polypeptide which may be secreted.
Journal ArticleDOI
Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity.
Patrick W. Gray,Bharat B. Aggarwal,Charles V. Benton,Timothy S. Bringman,William J. Henzel,Julie A. Jarrett,David W. Leung,Barbara Moffat,Peter Ng,L. P. Svedersky,Michael A. Palladino,Glenn Evan Nedwin +11 more
TL;DR: Purified recombinant lymphotoxin shows cytotoxic activity on murine and human tumour cell lines in vitro and causes necrosis of certain murine sarcomas in vivo.
Journal ArticleDOI
The murine transforming growth factor-beta precursor.
TL;DR: Two areas of the precursor exhibit a marked degree of homology to the human counterpart and suggests an important biological function for this area of TGF-beta, which can act, often in cooperation with other growth factors, as a mitogenic factor for a variety of cells.