J
Julien F. Biebuyck
Researcher at University of Wisconsin-Madison
Publications - 1
Citations - 151
Julien F. Biebuyck is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Myofilament & Halothane. The author has an hindex of 1, co-authored 1 publications receiving 146 citations.
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Anesthetic depression of myocardial contractility: a review of possible mechanisms.
TL;DR: The bulk of experimental evidence indicates that anesthetics do not produce their negative inotropic effect via an inhibitory action on mitochondrial electron transport, but the experimental act of removing myofibrils from their intracellular environment, or of removing the sarcolemma or making it hyperpermeable, appears to prevent some regulatory my ofibrillar phosphorylation reactions from taking place.