Showing papers by "Julien Nicolas published in 2006"
TL;DR: In this article, the SG1-based methyl methacrylate polymer was characterized and the presence of SG 1-based alkoxyamine at the polymer chain end was identified, supporting the livingness of the macromolecules.
Abstract: This article follows a previous study (Macromolecules 2005, 38, 5485) demonstrating that the nitroxide SG1-mediated polymerization of methyl methacrylate can be achieved at 90 °C with high conversion and high quality of control by introducing a small amount of styrene. In this work, the resulting polymer was characterized and the presence of SG1-based alkoxyamine at the polymer chain-end was identified, supporting the livingness of the macromolecules. In particular, it was shown that the alkoxyamine end group was connected to a single styrene terminal unit and that the methyl methacrylate penultimate unit had a strong effect on the temperature of dissociation. Consequently, the copolymerization of methyl methacrylate with a low molar proportion of styrene could be performed at temperatures below 90 °C. The polymer was also used as an efficient macroinitiator in the polymerization of styrene and n-butyl acrylate, to form methyl methacrylate-based block copolymers.
210 citations
TL;DR: BSA and lysozyme have been transformed into macroinitiators for living radical polymerisation and used to produce well-defined bioconjugates which can be fluorescently labelled providing a versatile strategy for the preparation of biocon conjugates which is complementary to traditional PEGylation.
134 citations
TL;DR: When the diblock copolymers become strongly asymmetrical, with a short poly(sodium acrylate) block and a long hydrophobic one, the formed hairy nanoparticles are analogous to amphiphilic dibock copolymer crew-cut micelles.
Abstract: The simple, one step synthesis of aqueous suspensions of amphiphilic nanoparticles is presented. Those particles are prepared in the batch heterophase polymerization of styrene or n-butyl acrylate, using a water-soluble poly(sodium acrylate) alkoxyamine macroinitiator. The nitroxide-mediated controlled growth of the hydrophobic block leads to the formation of poly(sodium acrylate)-b-polystyrene or poly(sodium acrylate)-b-poly(n-butyl acrylate) amphiphilic diblock copolymers, able to self-assemble in water simultaneously to the growth step. When the diblock copolymers become strongly asymmetrical, with a short poly(sodium acrylate) block and a long hydrophobic one, the formed hairy nanoparticles are analogous to amphiphilic diblock copolymer crew-cut micelles.
98 citations
TL;DR: In this paper, Nitroxide-mediated emulsion polymerizations of n-butyl acrylate and styrene were performed with a monofunctional, water-soluble alkoxyamine initiator and a difunctional one.
Abstract: Nitroxide-mediated emulsion polymerizations of n-butyl acrylate and styrene were performed with a monofunctional, water-soluble alkoxyamine initiator and a difunctional one. Two different processes were applied, either in two steps or under semibatch conditions. In particular, the polymerization times were strongly reduced, while high conversions and good control over the polymer characteristics were maintained. In all cases, stable latexes were recovered; with the difunctional initiator in particular, they exhibited small particles and narrow particle size distributions. © 2006 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 44: 4142–4153, 2006
53 citations
Journal Article•
TL;DR: In this paper, a simple one-step synthesis of aqueous suspensions of amphiphilic nanoparticles is presented, where the particles are prepared in the batch heterophase polymerization of styrene or n-butyl acrylate, using a water-soluble poly(sodium acrylated) alkoxyamine macroinitiator.
Abstract: The simple, one step synthesis of aqueous suspensions of amphiphilic nanoparticles is presented. Those particles are prepared in the batch heterophase polymerization of styrene or n-butyl acrylate, using a water-soluble poly(sodium acrylate) alkoxyamine macroinitiator. The nitroxide-mediated controlled growth of the hydrophobic block leads to the formation of poly(sodium acrylate)-b-polystyrene or poly(sodium acrylate)-b-poly(n-butyl acrylate) amphiphilic diblock copolymers, able to self-assemble in water simultaneously to the growth step. When the diblock copolymers become strongly asymmetrical, with a short poly(sodium acrylate) block and a long hydrophobic one, the formed hairy nanoparticles are analogous to amphiphilic diblock copolymer crew-cut micelles.
7 citations
Patent•
20 Nov 2006TL;DR: In this paper, a method for preparing a living polymer comprising methacrylic and/or methacrylate units using a monofunctional or polyfunctional alkoxyamine consisting in polymerising one or several types of methac acrylic and methacric monomers in the presence of at least one type of styrenic monomer is described.
Abstract: The invention relates to a method for preparing a living polymer comprising methacrylic and/or methacrylate units using a monofunctional or polyfunctional alkoxyamine consisting in polymerising one or several types of methacrylic and/or methacrylate monomers in the presence of at least one type of styrenic monomer.
5 citations
Patent•
20 Nov 2006
TL;DR: In this paper, the presente invention is a procedure for preparation of polymers for polymers, comprenant des unites methacryliques et/ou methacellates mettant en œuvre an alcoxyamine monofonctionnelle ou a polyf on conditionnelle, in presence of monomere styrenique.
Abstract: La presente invention a trait a un procede de preparation d'un polymere vivant comprenant des unites methacryliques et/ou methacrylates mettant en œuvre une alcoxyamine monofonctionnelle ou une alcoxyamine polyf onctionnelle, lequel procede comprenant une etape de polymerisation du ou des monomere methacryliques et/ou methacrylates en presence d'au moins un monomere styrenique.