Julius Andove

TL;DR: Proximity to the lake and contact with lake water were associated with infection, as were specific water-related activities including swimming, fishing, and collecting water.

TL;DR: Immunological resistance to reinfection with S mansoni exists or can develop independent of age effects, and the consequence of HIV-1 co-infection suggests that CD4 T cells contribute to this resistance.

TL;DR: Treatment of schistosomiasis was not associated with a reduction in plasma HIV-1 load and the time interval between pretreatment and follow-up samples, and the possibility of an adverse effect of helminthic infections on HIV- 1 pathogenesis is excluded.

TL;DR: Data fromitudinal investigations of an adult male population of Kenyan car washers who have heavy and quantifiable occupational exposure to Schistosoma mansoni cercariae implicate eosinophils as having a potential role in development of protective immunity against schistosomes and suggest that changes associated with HIV-1 coinfection increase susceptibility to reinfection.

TL;DR: Serum levels of polyclonal IgE were inversely correlated with percentages of CD117(+) cells regardless of HIV-1 status, suggesting that immature mast cells may affect IgE availability, or IgE may affect immaturemast cells, altering the balance of host susceptibility and resistance to schistosomes.